{"id":"W2102869951","doi":"10.1530/rep-13-0359","title":"Long exposure to mature ooplasm can alter DNA methylation at imprinted loci in non-growing oocytes but not in prospermatogonia","year":2013,"lang":"en","type":"article","venue":"Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Tokyo University of Agriculture; Ministry of Education, Culture, Sports, Science and Technology; Institute of Genetics; Naito Foundation","keywords":"Genomic imprinting; DNA methylation; Biology; Differentially methylated regions; Methylation; Epigenome; Epigenetics; Chromatin; Imprinting (psychology); Oocyte; Gamete; Oogenesis; Genetics; Cell biology; DNA; Sperm; Gene; Gene expression; Embryo","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009189911,0.0001374773,0.0001591148,0.0001020347,0.00008121772,0.0001841001,0.000155828,0.0001481337,0.0009867925],"category_scores_gemma":[0.0001286228,0.0001063346,0.000163689,0.00005881698,0.0001415321,0.000135268,0.000205454,0.000307368,0.0001911165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001266925,"about_ca_system_score_gemma":0.0001166098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000536249,"about_ca_topic_score_gemma":0.0008362122,"domain_scores_codex":[0.9999177,0.00000829226,0.000006743527,0.00002967874,0.00002170391,0.00001579714],"domain_scores_gemma":[0.9998699,0.00002398287,0.00004039326,0.00001878169,0.00001453604,0.00003238316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002561598,0.000002158248,0.0002509613,0.000006860989,0.000001564756,0.00002090253,0.00001197441,0.000003173792,0.9993594,0.00001316622,0.000003434893,0.000300806],"study_design_scores_gemma":[0.00001238342,0.0004501955,0.06841204,0.000006252411,0.00002295975,0.0003662657,0.0001057408,0.0002091475,0.928363,0.0000670685,0.001978794,0.000006259027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971336,0.001102724,0.0009058851,0.00002774427,0.00001711051,0.000008747689,0.0001771002,0.0000168299,0.0006102485],"genre_scores_gemma":[0.9957854,0.0004959186,0.000805481,0.00003586841,0.000007325488,0.00001645251,0.0004568826,0.00001681811,0.002379849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009867925,"threshold_uncertainty_score":0.003301144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007340188973842499,"score_gpt":0.2392226667141059,"score_spread":0.2318824777402634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}