{"id":"W2102869951","doi":"10.1530/rep-13-0359","title":"Long exposure to mature ooplasm can alter DNA methylation at imprinted loci in non-growing oocytes but not in prospermatogonia","year":2013,"lang":"en","type":"article","venue":"Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Tokyo University of Agriculture; Ministry of Education, Culture, Sports, Science and Technology; Institute of Genetics; Naito Foundation","keywords":"Genomic imprinting; DNA methylation; Biology; Differentially methylated regions; Methylation; Epigenome; Epigenetics; Chromatin; Imprinting (psychology); Oocyte; Gamete; Oogenesis; Genetics; Cell biology; DNA; Sperm; Gene; Gene expression; Embryo","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003835734,0.0001676468,0.0001601969,0.0001445827,0.00005527548,0.00003738796,0.00008762764,0.0002105401,0.00002218624],"category_scores_gemma":[0.0001662845,0.0001704474,0.00004803883,0.0002378287,0.00001965178,0.00002192824,0.00009794698,0.0001387003,0.00003180871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001156028,"about_ca_system_score_gemma":0.00002821167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000345334,"about_ca_topic_score_gemma":0.0006312517,"domain_scores_codex":[0.9985049,0.00007441898,0.0003405187,0.000674595,0.0001473404,0.0002582429],"domain_scores_gemma":[0.9992202,0.00000696655,0.00009206292,0.0004886726,0.0001256292,0.00006645743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005376063,0.00003234532,0.03476489,0.00002722543,0.000008582577,0.000001508233,0.0002274784,0.002109331,0.9546444,0.000003303139,0.00005578047,0.008071342],"study_design_scores_gemma":[0.0002655178,0.00008025615,0.272689,0.00001803492,0.000003902085,0.000004647616,0.00004183976,0.0001523841,0.7260637,0.00003681796,0.0004961912,0.000147732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970364,0.0004678105,0.0005245887,0.0009333596,0.000252078,0.0006793566,0.000003746989,0.0000149301,0.00008773591],"genre_scores_gemma":[0.9977443,0.00009875754,0.0006937159,0.00008572991,0.0003138034,0.0001109563,0.0001547758,0.0000283524,0.000769635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2379241,"threshold_uncertainty_score":0.6950644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007340188973842499,"score_gpt":0.2392226667141059,"score_spread":0.2318824777402634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}