{"id":"W2102886247","doi":"10.1210/en.2006-1542","title":"Reporter Expression, Induced by a Growth Hormone Promoter-Driven Cre Recombinase (rGHp-Cre) Transgene, Questions the Developmental Relationship between Somatotropes and Lactotropes in the Adult Mouse Pituitary Gland","year":2007,"lang":"en","type":"article","venue":"Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"U.S. Public Health Service","keywords":"Cre recombinase; Somatotropic cell; Internal medicine; Endocrinology; Transgene; Biology; Pituitary gland; Genetically modified mouse; Growth hormone; Prolactin; Hormone; Gene; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003543776,0.0003290504,0.0004361827,0.0002533703,0.0003679883,0.00003477128,0.000256399,0.000219555,0.0000149236],"category_scores_gemma":[0.0004197422,0.0001996668,0.00008256607,0.0003407274,0.0002332568,0.0002232963,0.00007911611,0.0008083497,0.00001385917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008259402,"about_ca_system_score_gemma":0.0001102078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004585732,"about_ca_topic_score_gemma":0.0001787871,"domain_scores_codex":[0.9974693,0.0003001816,0.0007922308,0.0004804631,0.0002984169,0.0006593809],"domain_scores_gemma":[0.9986882,0.0004726092,0.0001781283,0.0003777019,0.0001133602,0.000169989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002518656,0.0003008336,0.9458683,0.00004279311,0.00008407624,0.0003207043,0.004616475,1.116067e-7,0.04343709,0.0005636748,0.003259003,0.001255137],"study_design_scores_gemma":[0.002553536,0.0005294702,0.9744494,0.00004747758,0.0001010664,0.0006342399,0.00133379,0.000002214131,0.01814538,0.0005046211,0.001443656,0.0002551525],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923584,0.0006382859,0.0001963307,0.004845525,0.00007044502,0.0009443896,0.00002951269,0.00009631775,0.0008208319],"genre_scores_gemma":[0.9977887,0.0001983587,0.0007321294,0.0006669953,0.0001184753,0.0001040852,0.0001777751,0.00004012116,0.0001733903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02858116,"threshold_uncertainty_score":0.8142175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02910595778233553,"score_gpt":0.2729223824745398,"score_spread":0.2438164246922043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}