{"id":"W2102886247","doi":"10.1210/en.2006-1542","title":"Reporter Expression, Induced by a Growth Hormone Promoter-Driven Cre Recombinase (rGHp-Cre) Transgene, Questions the Developmental Relationship between Somatotropes and Lactotropes in the Adult Mouse Pituitary Gland","year":2007,"lang":"en","type":"article","venue":"Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"U.S. Public Health Service","keywords":"Cre recombinase; Somatotropic cell; Internal medicine; Endocrinology; Transgene; Biology; Pituitary gland; Genetically modified mouse; Growth hormone; Prolactin; Hormone; Gene; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004034479,0.0002886331,0.0002408393,0.0002337754,0.0001283048,0.0006061104,0.0004250926,0.00056702,0.001104106],"category_scores_gemma":[0.000278801,0.0002881124,0.0002469768,0.0001255734,0.0005715597,0.0005903032,0.0002945471,0.001106071,0.0006289533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002701122,"about_ca_system_score_gemma":0.000315801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005140366,"about_ca_topic_score_gemma":0.0007544847,"domain_scores_codex":[0.9997725,0.00002355208,0.00002340345,0.00005274241,0.00008693076,0.00004103073],"domain_scores_gemma":[0.9996617,0.00009414992,0.0001228096,0.00004032824,0.00003124848,0.00004972284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004075966,0.00000963526,0.0004464758,0.00003684555,0.000002855583,0.00006071469,0.00003289885,0.00003344919,0.9972724,0.0004766435,0.000031527,0.001555792],"study_design_scores_gemma":[0.00002483745,0.0003101708,0.007415227,0.00003676602,0.00002655721,0.001080553,0.0001622612,0.0008862549,0.9787961,0.0004077957,0.01084376,0.000009628141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9437409,0.003776951,0.04708092,0.000751577,0.0001075285,0.00007464229,0.0009716672,0.0005953305,0.002900442],"genre_scores_gemma":[0.9644416,0.004683267,0.02407699,0.000290352,0.00006261852,0.0001007846,0.001034032,0.000155369,0.005154889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001104106,"threshold_uncertainty_score":0.00369364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02910595778233553,"score_gpt":0.2729223824745398,"score_spread":0.2438164246922043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}