{"id":"W2102886762","doi":"","title":"Development and validation of a sensitive and specific HPLC assay of cladribine for pharmacokinetics studies in rats.","year":2007,"lang":"en","type":"article","venue":"PubMed","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chromatography; High-performance liquid chromatography; Pharmacokinetics; Chemistry; Cladribine; Coefficient of variation; Standard curve; Extraction (chemistry); Pharmacology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001639638,0.001559263,0.0007847725,0.0007806516,0.000360807,0.0004011834,0.000630649,0.0008119119,0.001125133],"category_scores_gemma":[0.0009950451,0.0005672321,0.0006005982,0.0004053233,0.0005310949,0.0006145074,0.0003260566,0.000912156,0.0009488974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006701474,"about_ca_system_score_gemma":0.001175797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001093384,"about_ca_topic_score_gemma":0.002353822,"domain_scores_codex":[0.9990441,0.0002085133,0.00008227226,0.0002333297,0.0003517708,0.00007994989],"domain_scores_gemma":[0.9990432,0.0001302337,0.0002777145,0.0001546551,0.0002770875,0.0001170703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001971218,0.00009760422,0.0004365362,0.0001575665,0.00002083726,0.00003920273,0.0000134848,0.0001825153,0.9890783,0.00007670283,0.00009320693,0.009606856],"study_design_scores_gemma":[0.00005308195,0.001999514,0.003984394,0.0000271643,0.00006812653,0.0004578886,0.0000119072,0.001305257,0.9871723,0.00005680813,0.004844055,0.00001946736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5771399,0.02008513,0.3893219,0.0005709435,0.0004470091,0.001580683,0.003509327,0.002007752,0.005337453],"genre_scores_gemma":[0.7165201,0.01513328,0.2522899,0.0006573023,0.0002001104,0.001819185,0.004573205,0.0002079946,0.008598875],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001639638,"threshold_uncertainty_score":0.008671343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1132400557486244,"score_gpt":0.3591494099913999,"score_spread":0.2459093542427755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}