{"id":"W2102915129","doi":"10.1016/j.mehy.2008.02.014","title":"Proteasome inhibition as a novel therapy in treating rheumatoid arthritis","year":2008,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Pannus; Medicine; Rheumatoid arthritis; Apoptosis; Cancer research; Proteasome; In vivo; Proteasome inhibitor; Multiple myeloma; Immunology; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007697638,0.0005722261,0.0007510999,0.0007434053,0.0005273143,0.0009937874,0.0005574161,0.0009997803,0.005052555],"category_scores_gemma":[0.0003217585,0.0002180228,0.000546435,0.0004338161,0.001014169,0.0008227128,0.0003504825,0.00231189,0.001200207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004211899,"about_ca_system_score_gemma":0.0005207902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003166059,"about_ca_topic_score_gemma":0.0009035058,"domain_scores_codex":[0.9998181,0.00006377232,0.00001706414,0.00002412937,0.00004615945,0.00003082323],"domain_scores_gemma":[0.9998657,0.00005438144,0.00003227881,0.00001058548,0.0000137192,0.00002337623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.01038521,0.00355245,0.002572116,0.003685288,0.0003564206,0.003630079,0.00026334,0.001545048,0.123988,0.04071795,0.03784374,0.7714603],"study_design_scores_gemma":[0.01212344,0.03452663,0.02857096,0.001151892,0.001602729,0.02148636,0.0006459323,0.005209989,0.1270326,0.05777325,0.7096071,0.0002692066],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1008805,0.8256466,0.005800023,0.0259752,0.005558697,0.0001377785,0.0003826393,0.0003338338,0.03528474],"genre_scores_gemma":[0.4855769,0.473435,0.007560349,0.00603496,0.006358215,0.0001549315,0.0003587444,0.00002802317,0.02049287],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005052555,"threshold_uncertainty_score":0.01690251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05521311205147472,"score_gpt":0.3094880683078491,"score_spread":0.2542749562563744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}