{"id":"W2102918226","doi":"10.1074/jbc.m410113200","title":"Family 6 Carbohydrate Binding Modules Recognize the Non-reducing End of β-1,3-Linked Glucans by Presenting a Unique Ligand Binding Surface","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Laminarin; Carbohydrate-binding module; Binding site; Ligand (biochemistry); Affinities; Chemistry; Biochemistry; Structural similarity; Stereochemistry; Enzyme; Glycoside hydrolase; Hydrolase; Polysaccharide; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004525046,0.0001584125,0.0002303985,0.00001946065,0.0001031185,0.00003114622,0.0002554145,0.0002352917,0.0000107147],"category_scores_gemma":[0.0002511314,0.0001061368,0.0001416057,0.0001487312,0.0001392315,0.00001116101,0.00008122932,0.0002662577,7.986651e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003188825,"about_ca_system_score_gemma":0.00008474738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001127407,"about_ca_topic_score_gemma":4.316994e-7,"domain_scores_codex":[0.9988818,0.00004974244,0.0004939037,0.0002263714,0.0001427548,0.0002054581],"domain_scores_gemma":[0.9989572,0.00002667575,0.0005868982,0.0001706096,0.0001794723,0.00007918387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005723369,0.00006610775,0.001321571,0.00002985901,0.00006311408,0.000003095987,0.0000621817,0.0004418197,0.9976404,0.000001049925,0.0001256847,0.0001878593],"study_design_scores_gemma":[0.0004189834,0.00009636465,0.0009553361,0.00007390035,0.0000211173,0.0000518019,0.0002538903,0.00002222069,0.9974208,0.00002933759,0.0005269184,0.0001293295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982084,0.0004734556,0.0005149053,0.0003781993,0.0001472344,0.00007848282,0.00002727245,0.000006415384,0.0001656583],"genre_scores_gemma":[0.9980346,0.000801147,0.0005216476,0.00004906105,0.0003377312,0.000001854502,0.00007406379,0.00001326152,0.0001666344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000419599,"threshold_uncertainty_score":0.4328135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01817487877675319,"score_gpt":0.24700015333292,"score_spread":0.2288252745561668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}