{"id":"W2102922603","doi":"10.1016/j.bmcl.2007.04.069","title":"Synthesis and biodistribution of 8-iodo-11-(4-methylpiperazino)-5H-dibenzo[b,e][1,4]-diazepine: Iozapine","year":2007,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Biodistribution; Chemistry; Diazepine; Ligand (biochemistry); Chemical synthesis; Stereochemistry; Receptor; In vitro; Organic chemistry; Biochemistry; Ring (chemistry)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001534569,0.0003172637,0.0002271189,0.0002622718,0.0001614459,0.0002649695,0.0004529637,0.0002763035,0.001456292],"category_scores_gemma":[0.0001579199,0.0001856016,0.0001364898,0.0001616976,0.0001771629,0.0001868071,0.0001477053,0.0003838141,0.0008802082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003824559,"about_ca_system_score_gemma":0.0004394622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002323987,"about_ca_topic_score_gemma":0.002343024,"domain_scores_codex":[0.9999294,0.000009319169,0.00000516127,0.00001677993,0.00001275771,0.00002663957],"domain_scores_gemma":[0.9999207,0.00001257704,0.00001770703,0.00001345226,0.00001162969,0.00002383308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002173348,0.00003344352,0.00005902218,0.00002806508,0.000005451108,0.00008084389,0.00002273896,0.0002015588,0.9966642,0.0002396747,0.00006638656,0.002381197],"study_design_scores_gemma":[0.00003699851,0.0002493231,0.00058271,0.000002548628,0.00002110831,0.0001367394,0.00001102533,0.0005696694,0.9946594,0.00003883265,0.003686837,0.000004769749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9321012,0.002722318,0.04246211,0.000401211,0.0001543846,0.0002755715,0.001878384,0.0006800462,0.01932476],"genre_scores_gemma":[0.972403,0.001542484,0.01154038,0.00006037821,0.00002041465,0.00006096666,0.0009049743,0.00009571646,0.01337166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002323987,"threshold_uncertainty_score":0.004871786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02815642246672834,"score_gpt":0.2991747143870593,"score_spread":0.271018291920331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}