{"id":"W2102923747","doi":"10.1128/mcb.01620-06","title":"RECQL, a Member of the RecQ Family of DNA Helicases, Suppresses Chromosomal Instability","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Columbia College","funders":"National Institute of Environmental Health Sciences; National Institute on Aging; National Institutes of Health","keywords":"Biology; Genome instability; RecQ helicase; Bloom syndrome; Genetics; Chromosome instability; Phenotype; DNA damage; DNA repair; Helicase; Chromothripsis; Molecular biology; Gene; DNA; Cell biology; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002032843,0.0005301941,0.0002582614,0.0005511874,0.0001182725,0.0003669439,0.0003880748,0.0003236644,0.001413072],"category_scores_gemma":[0.0002121562,0.0001858081,0.0002446015,0.0001831174,0.0002632755,0.0001845877,0.0002729097,0.0004324573,0.0004053641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001881346,"about_ca_system_score_gemma":0.0001509152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002971851,"about_ca_topic_score_gemma":0.0004629095,"domain_scores_codex":[0.9998021,0.00003515091,0.00002227454,0.00003745369,0.00005869085,0.00004444258],"domain_scores_gemma":[0.9997203,0.00003262224,0.00009114682,0.00004718769,0.00002129956,0.00008740053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008120213,0.0000204142,0.0001394678,0.00001539069,0.000004192817,0.00006258916,0.000005631891,0.00003350517,0.9981626,0.0000881566,0.0000308367,0.001356072],"study_design_scores_gemma":[0.00004270025,0.0003927646,0.002762359,0.000006572245,0.00001479235,0.0005316,0.00001531403,0.0004855346,0.992898,0.00007220489,0.00277353,0.000004606924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930353,0.001644538,0.003210632,0.0001068868,0.00002696842,0.00001824659,0.0002929387,0.0002949185,0.001369491],"genre_scores_gemma":[0.9901155,0.001080194,0.001909106,0.00004823362,0.00001573508,0.00002388017,0.0006334001,0.00007000336,0.006103959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001413072,"threshold_uncertainty_score":0.004727185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00700189484552179,"score_gpt":0.2143564700068761,"score_spread":0.2073545751613543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}