{"id":"W2102923747","doi":"10.1128/mcb.01620-06","title":"RECQL, a Member of the RecQ Family of DNA Helicases, Suppresses Chromosomal Instability","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Columbia College","funders":"National Institute of Environmental Health Sciences; National Institute on Aging; National Institutes of Health","keywords":"Biology; Genome instability; RecQ helicase; Bloom syndrome; Genetics; Chromosome instability; Phenotype; DNA damage; DNA repair; Helicase; Chromothripsis; Molecular biology; Gene; DNA; Cell biology; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002134151,0.0001851869,0.0002752477,0.00003191923,0.00004625267,0.000005109762,0.0002577895,0.0002693238,0.00002198341],"category_scores_gemma":[0.00007855731,0.0001411356,0.0001860918,0.0001171839,0.000385458,0.00000245556,0.0002298521,0.00008420582,9.862625e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007022914,"about_ca_system_score_gemma":0.00006885111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002005517,"about_ca_topic_score_gemma":0.00003456385,"domain_scores_codex":[0.9986266,0.0002613205,0.0003572047,0.000412081,0.0001053014,0.0002374781],"domain_scores_gemma":[0.999017,0.00001719913,0.0001641346,0.0006561172,0.0001032151,0.00004231143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005472709,0.000108247,0.003060884,0.00004758437,0.00004280735,0.000004258705,0.00001075538,0.000008567994,0.994636,0.001589043,0.0001072929,0.0003298277],"study_design_scores_gemma":[0.0003990107,0.0003054394,0.001052595,0.00001244935,0.00003889618,0.00001913289,0.00002835868,0.00001524927,0.9886639,0.001105984,0.008211609,0.000147359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928803,0.003355946,0.001289624,0.00005965315,0.0001287738,0.000247901,0.00007217942,0.000009428985,0.001956172],"genre_scores_gemma":[0.9989833,0.00004108808,0.0005599968,0.0001000582,0.00004655492,0.00001701788,0.0001166268,0.0000202648,0.0001151088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008104316,"threshold_uncertainty_score":0.5755345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00700189484552179,"score_gpt":0.2143564700068761,"score_spread":0.2073545751613543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}