{"id":"W2102928582","doi":"10.1099/vir.0.028746-0","title":"Inefficient fusion due to a lack of attachment receptor/co-receptor restricts productive human immunodeficiency virus type 1 infection in human hepatoma Huh7.5 cells","year":2010,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Institute of Genetics; Canada Research Chairs","keywords":"Biology; Virology; Virus; In vitro; Human immunodeficiency virus (HIV); Receptor; Viral entry; Immunology; In vivo; CXCR4; Cell fusion; Cell; Viral replication; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003132516,0.0001732617,0.0003256192,0.0001977634,0.0001780651,0.0006091683,0.0001608593,0.0001679055,0.0008285278],"category_scores_gemma":[0.0002286658,0.0001823007,0.0002291979,0.0001838691,0.0002255922,0.0002376942,0.0002734345,0.0003447391,0.0004659551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002996303,"about_ca_system_score_gemma":0.0002756011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002708168,"about_ca_topic_score_gemma":0.002589251,"domain_scores_codex":[0.9996638,0.00008070239,0.00004701837,0.00003459783,0.00009989203,0.00007396132],"domain_scores_gemma":[0.9997392,0.0001158096,0.00002742032,0.00006030138,0.00002505505,0.0000321983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001413823,0.0000548726,0.0009124938,0.00004303423,0.000009545635,0.00009941831,0.00006462021,0.0001404791,0.9970907,0.0002628976,0.00007758316,0.001103117],"study_design_scores_gemma":[0.00004682593,0.001261199,0.01676484,0.00002022425,0.00004183745,0.0009941095,0.0002230287,0.003611448,0.9720453,0.0001758794,0.004798323,0.00001693235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949247,0.001184751,0.001730676,0.00005831832,0.00001691822,0.00002464951,0.0002015269,0.00003296981,0.001825413],"genre_scores_gemma":[0.9968477,0.0006998444,0.0008913843,0.00003169134,0.000006930806,0.00001562802,0.0004920615,0.000009801408,0.001004923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002708168,"threshold_uncertainty_score":0.005384862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02545682720923534,"score_gpt":0.3320305724943446,"score_spread":0.3065737452851093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}