{"id":"W2102979288","doi":"10.1101/cshperspect.a014373","title":"c-MYC-Induced Genomic Instability","year":2014,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Medicine","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Genome instability; Biology; Gerontology; Genetics; Medicine; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001062303,0.0005753798,0.00168103,0.0002620212,0.00006113133,0.00001471876,0.00066834,0.0005513822,0.00005056231],"category_scores_gemma":[0.0009649122,0.0005022946,0.0003292535,0.0002652087,0.0002155614,0.000003571084,0.0003267525,0.0005906411,0.00003171569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004086644,"about_ca_system_score_gemma":0.0003112023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006303144,"about_ca_topic_score_gemma":0.00003423195,"domain_scores_codex":[0.997042,0.0003334935,0.0006916742,0.001212314,0.0002549028,0.0004656117],"domain_scores_gemma":[0.9980183,0.00007307781,0.0003149191,0.001331992,0.00009798697,0.0001637113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002735851,0.001548743,0.0004905162,0.04895626,0.002402102,0.0002932399,0.002044914,0.00001254343,0.5522174,0.09415071,0.001148264,0.2964617],"study_design_scores_gemma":[0.0006921422,0.0004413338,0.000230117,0.00446821,0.0002509857,0.000005367882,0.0001542323,0.000008617852,0.0009423702,0.00002219456,0.9921644,0.0006200671],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006710748,0.9902328,0.0001951431,0.00004446104,0.000570407,0.0009999588,0.000007162344,0.00005222208,0.001187135],"genre_scores_gemma":[0.02696412,0.9708996,0.0004049823,0.00005813206,0.001241979,0.0001824264,0.000009474315,0.000122756,0.000116533],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9910161,"threshold_uncertainty_score":0.9997429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03372216489719538,"score_gpt":0.3240943270160985,"score_spread":0.2903721621189031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}