{"id":"W2103072285","doi":"10.1016/j.bbagen.2015.04.014","title":"IDH1, lipid metabolism and cancer: Shedding new light on old ideas","year":2015,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"University of Toronto","keywords":"IDH1; Isocitrate dehydrogenase; Lipid metabolism; Biology; Peroxisome; Cancer research; Cancer; Biochemistry; Mutant; Enzyme; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006855093,0.0007168105,0.001407865,0.001706506,0.0003364235,0.001233397,0.0009111926,0.001412613,0.003021662],"category_scores_gemma":[0.0007870503,0.0002528929,0.0003707542,0.002054452,0.0007427746,0.001477157,0.0009285818,0.002055042,0.001165464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007791254,"about_ca_system_score_gemma":0.001429357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001380819,"about_ca_topic_score_gemma":0.00298282,"domain_scores_codex":[0.9998658,0.00002166998,0.00001596266,0.0000260476,0.00005206409,0.00001840676],"domain_scores_gemma":[0.9997135,0.0001358424,0.00003047755,0.000009521784,0.00007273485,0.0000378971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001666628,0.00006228474,0.0004367361,0.01382446,0.0001228655,0.0003180472,0.00009553676,0.0003896041,0.002024396,0.008708008,0.08496537,0.888886],"study_design_scores_gemma":[0.00001897079,0.00003833751,0.0006409056,0.001836034,0.00009615179,0.0007710935,0.00007386197,0.00007107174,0.0002921292,0.003245487,0.9928966,0.00001933907],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005715921,0.9989043,0.00005903418,0.0003896761,0.0002162903,9.923913e-7,0.00001403092,0.000003969236,0.0003545055],"genre_scores_gemma":[0.000480574,0.9984319,0.00008983087,0.0002950878,0.000328405,0.000002133144,0.00002383648,8.677759e-7,0.000347375],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003021662,"threshold_uncertainty_score":0.01010847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0241866560546217,"score_gpt":0.307010404680109,"score_spread":0.2828237486254873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}