{"id":"W2103188373","doi":"10.1002/psc.704","title":"Function and therapeutic potential of host defence peptides","year":2005,"lang":"en","type":"review","venue":"Journal of Peptide Science","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":182,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Genome Prairie; Canada Research Chairs; Canadian Institutes of Health Research; Genome British Columbia; Cystic Fibrosis Foundation","keywords":"Innate immune system; Antimicrobial; Antimicrobial peptides; Host (biology); Function (biology); Immune system; Immunity; Biology; Broad spectrum; Computational biology; Microbiology; Chemistry; Immunology; Cell biology; Ecology; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004943949,0.0006913847,0.0007844304,0.001304231,0.0002116489,0.0009125685,0.0006204004,0.001010614,0.002363465],"category_scores_gemma":[0.0004248338,0.000169617,0.0002688812,0.0008042756,0.0003976079,0.001042852,0.0004591962,0.001545047,0.001735734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004507592,"about_ca_system_score_gemma":0.0003483136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002591061,"about_ca_topic_score_gemma":0.0004188927,"domain_scores_codex":[0.9998523,0.00002700472,0.00001579805,0.00002685735,0.00006137627,0.00001654938],"domain_scores_gemma":[0.9998838,0.00004477183,0.00001568631,0.000005488791,0.00003404509,0.00001612464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001270789,0.0001075541,0.0001623288,0.005338803,0.00004428381,0.0005984498,0.00007035103,0.0004899703,0.01556279,0.007790382,0.01706383,0.9526442],"study_design_scores_gemma":[0.0000331734,0.0001824834,0.0006709268,0.001161639,0.00003088414,0.0030515,0.00004393014,0.0001381644,0.00286142,0.003027946,0.9887828,0.00001504518],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004464393,0.9965856,0.0002299348,0.0002291337,0.0002856353,0.00000424241,0.000009730822,0.000006371285,0.002202848],"genre_scores_gemma":[0.00320941,0.9927381,0.0005979735,0.0003694735,0.0003497908,0.00001387871,0.00003029534,0.00000212923,0.002689024],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002363465,"threshold_uncertainty_score":0.007906616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02566441986938703,"score_gpt":0.2866647342100952,"score_spread":0.2610003143407081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}