{"id":"W2103192992","doi":"10.1042/bj20101375","title":"Protein 4.2 interaction with hereditary spherocytosis mutants of the cytoplasmic domain of human anion exchanger 1","year":2010,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Band 3; Biology; Cytoplasm; Hereditary spherocytosis; Mutant; HEK 293 cells; Subcellular localization; Mutant protein; Endoplasmic reticulum; Wild type; Transport protein; Vesicle-associated membrane protein 8; Membrane protein; Protein subcellular localization prediction; Molecular biology; Cell biology; Gene isoform; Biochemistry; Gene; Genetics; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001135082,0.00009430287,0.0002056479,0.00004338253,0.00005565964,0.000003669336,0.00008512125,0.0001271391,0.000474775],"category_scores_gemma":[0.00004243141,0.00005331287,0.0001012088,0.0001171658,0.0001585938,0.00004079006,0.00002861421,0.0005734554,0.000003620201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002592325,"about_ca_system_score_gemma":0.00006095248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009236377,"about_ca_topic_score_gemma":0.000008875059,"domain_scores_codex":[0.9992614,0.00004317151,0.000258263,0.0001085567,0.0002102345,0.0001183201],"domain_scores_gemma":[0.9993436,0.00001917919,0.0002442571,0.0001746204,0.0001357677,0.0000825972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000646779,0.0001486706,0.00192686,0.00004917254,0.00003860113,0.000009316632,0.00009632369,1.987339e-7,0.9957113,0.00001926214,0.0009419639,0.0004115803],"study_design_scores_gemma":[0.001175911,0.0006252215,0.009806053,0.0002730749,0.0000392382,0.001358149,0.0002301174,0.000005517302,0.9858527,0.0001509436,0.0004230705,0.00006001528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987174,0.00003512231,0.00004857168,0.0003285923,0.000343812,0.0001553967,0.000004180348,0.00000800011,0.000358911],"genre_scores_gemma":[0.998304,0.000005705049,0.0009748895,0.00008377741,0.0005127713,0.000004062516,0.000004424117,0.0000113659,0.00009901867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009858582,"threshold_uncertainty_score":0.5198453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376288579515582,"score_gpt":0.2582484775942376,"score_spread":0.2444855917990818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}