{"id":"W2103290564","doi":"10.1186/bcr3411","title":"Is TIMP-1 immunoreactivity alone or in combination with other markers a predictor of benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial?","year":2013,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Surgical oncology; Medicine; Breast cancer; Oncology; Internal medicine; Adjuvant; Adjuvant chemotherapy; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004919454,0.0006376794,0.00198874,0.0003353316,0.0001844582,0.0009063809,0.0005667506,0.0009840979,0.002525749],"category_scores_gemma":[0.003270841,0.0002670198,0.001071104,0.0004525884,0.0005628759,0.0005736183,0.000308943,0.001562928,0.0004692419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003290567,"about_ca_system_score_gemma":0.0006609632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000211848,"about_ca_topic_score_gemma":0.0006517355,"domain_scores_codex":[0.9986884,0.0009731688,0.00007401377,0.00009986149,0.00008896105,0.00007560843],"domain_scores_gemma":[0.9967895,0.001649865,0.0008045895,0.000162633,0.00008420715,0.0005091419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8752772,0.001802299,0.04670761,0.0009423289,0.002058192,0.0001215292,0.00007764559,0.001335302,0.008522274,0.0001594485,0.001183163,0.0618129],"study_design_scores_gemma":[0.4829631,0.2850905,0.2024139,0.000734178,0.008624796,0.0008291244,0.0001098781,0.005731069,0.006035429,0.001125281,0.006220767,0.00012206],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863937,0.0096952,0.0002245924,0.001297553,0.0001419356,0.0002106336,0.0006866886,0.00001915642,0.001330443],"genre_scores_gemma":[0.9933282,0.002619367,0.0005127933,0.0006030469,0.0004642646,0.0003034853,0.001125072,0.00001060577,0.001033004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004919454,"threshold_uncertainty_score":0.02601689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02521374969241564,"score_gpt":0.3318421685016569,"score_spread":0.3066284188092413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}