{"id":"W2103323117","doi":"10.1158/1078-0432.ccr-08-3275","title":"Effective Treatment of Advanced Human Melanoma Metastasis in Immunodeficient Mice Using Combination Metronomic Chemotherapy Regimens","year":2009,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Cancer Institute; National Institutes of Health","keywords":"Medicine; Chemotherapy; Melanoma; Oncology; Metastasis; Cancer; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003497362,0.0007861669,0.0005419984,0.0005544525,0.0001795384,0.0003414552,0.0004772755,0.0004566238,0.001583444],"category_scores_gemma":[0.0001055262,0.0002224518,0.0003515978,0.0002148879,0.0003188365,0.00035533,0.0001655362,0.00104854,0.0003113018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000403839,"about_ca_system_score_gemma":0.0003569965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004710765,"about_ca_topic_score_gemma":0.0008211515,"domain_scores_codex":[0.9997217,0.00005379768,0.00002789095,0.00005737327,0.00007772003,0.0000614955],"domain_scores_gemma":[0.999833,0.00002291994,0.00005419804,0.00002616097,0.000009640376,0.00005399725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000809508,0.0006734924,0.0002042897,0.00008789138,0.00001834514,0.00004967795,0.00001271873,0.0003307765,0.9941626,0.000177819,0.0001432275,0.003329514],"study_design_scores_gemma":[0.0005292086,0.009313161,0.002233246,0.00002265673,0.0000631941,0.0004077852,0.00001320201,0.00205789,0.9815655,0.00007336903,0.003710629,0.00001011916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877994,0.002991951,0.004794923,0.000206239,0.0001115147,0.0003751205,0.001092408,0.0002602939,0.002368164],"genre_scores_gemma":[0.9866517,0.001764436,0.00702378,0.00009701532,0.00003893633,0.0003266311,0.001211238,0.00005307217,0.002833168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001583444,"threshold_uncertainty_score":0.005297184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1152284760962301,"score_gpt":0.4832665285959733,"score_spread":0.3680380524997432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}