{"id":"W2103483997","doi":"10.1158/1541-7786.mcr-10-0411","title":"Relaxin Enhances the Collagenolytic Activity and <i>In Vitro</i> Invasiveness by Upregulating Matrix Metalloproteinases in Human Thyroid Carcinoma Cells","year":2011,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Pregnancy-related medical research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"MMP2; Invadopodia; TIMP1; Matrix metalloproteinase; Cancer research; Gelatinase; Thyroid cancer; MMP1; Thyroid carcinoma; MMP9; Biology; Cancer cell; Metastasis; Thyroid; Cancer; Pathology; Cell biology; Downregulation and upregulation; Endocrinology; Medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656672,0.0003746943,0.000252365,0.0001450284,0.0001101801,0.0002378964,0.00008897336,0.0001684674,0.001050027],"category_scores_gemma":[0.0001022925,0.0001159262,0.0003108931,0.00009420238,0.0001407239,0.0001294346,0.0001355437,0.0004165225,0.0003344042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001994714,"about_ca_system_score_gemma":0.0001292444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000945611,"about_ca_topic_score_gemma":0.001406365,"domain_scores_codex":[0.9998592,0.00003246992,0.00001171133,0.00002342183,0.00003658136,0.00003656089],"domain_scores_gemma":[0.9999177,0.00001699752,0.00002009721,0.00001172133,0.00001182362,0.00002156057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004461896,0.00001395697,0.00006183596,0.00001845721,0.000002380582,0.00002959753,0.000009637304,0.00001206675,0.9994656,0.000009595933,0.00001995797,0.0003123989],"study_design_scores_gemma":[0.00001632087,0.0005471255,0.00437302,0.000004697187,0.00001771269,0.0003143265,0.00003847796,0.0004439225,0.9911923,0.00001187433,0.003035946,0.000004327842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927211,0.003107723,0.001804402,0.0001224308,0.00004277306,0.00003224811,0.0002479502,0.00007947093,0.001841823],"genre_scores_gemma":[0.9910812,0.001944507,0.002665302,0.0001019439,0.00002957629,0.00004707358,0.0008640027,0.00002096537,0.003245614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001050027,"threshold_uncertainty_score":0.003512681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0560540628506828,"score_gpt":0.3669193183603178,"score_spread":0.310865255509635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}