{"id":"W2103533222","doi":"10.1084/jem.20031637","title":"The BCR-ABL1 Kinase Bypasses Selection for the Expression of a Pre–B Cell Receptor in Pre–B Acute Lymphoblastic Leukemia Cells","year":2004,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Deutsche Krebshilfe; Universität zu Köln; Studienstiftung des Deutschen Volkes; Deutsche Forschungsgemeinschaft; Deutscher Akademischer Austauschdienst; Stem Cell Network","keywords":"Biology; breakpoint cluster region; B-cell receptor; Leukemia; ABL; Cancer research; Acute lymphocytic leukemia; CD135; B cell; Molecular biology; Receptor; Signal transduction; Cell biology; Antibody; Immunology; Tyrosine kinase; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000964168,0.0003134837,0.0002825406,0.0001456467,0.0001276173,0.0003473344,0.0002535421,0.0001772121,0.001518661],"category_scores_gemma":[0.0001006477,0.0002011292,0.0001975891,0.0001444895,0.0001602852,0.0001335649,0.0002219188,0.0008370186,0.0007631363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003252473,"about_ca_system_score_gemma":0.0002801981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001045962,"about_ca_topic_score_gemma":0.001515231,"domain_scores_codex":[0.9998724,0.0000191389,0.00001563185,0.00002097712,0.00004100776,0.0000308095],"domain_scores_gemma":[0.9999222,0.00001516992,0.00001989829,0.00001326957,0.000005834042,0.00002363508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004648589,0.00002272346,0.0001023528,0.00001861846,0.000002729065,0.00002987701,0.00001176616,0.00005421995,0.9989158,0.0001297518,0.00003465367,0.0006311336],"study_design_scores_gemma":[0.00002649984,0.0002974803,0.003474035,0.000005645737,0.00001422178,0.0004118537,0.00001805523,0.0006343471,0.9900066,0.0000401801,0.005066972,0.00000399338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947059,0.001185222,0.00159645,0.0001174758,0.00003226639,0.00005830556,0.0005358215,0.0001044957,0.001664135],"genre_scores_gemma":[0.9930289,0.001089992,0.001650428,0.00006264621,0.0000123247,0.00006202137,0.001036994,0.00003043338,0.003026274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001518661,"threshold_uncertainty_score":0.005080462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01187538561218665,"score_gpt":0.2927782146703131,"score_spread":0.2809028290581264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}