{"id":"W2103597375","doi":"10.1093/jac/dkt326","title":"Defective HIV-1 quasispecies in the form of multiply drug-resistant proviral DNA within cells can be rescued by superinfection with different subtype variants of HIV-1 and by HIV-2 and SIV","year":2013,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Viral quasispecies; Superinfection; Virology; Provirus; Biology; Human immunodeficiency virus (HIV); SAMHD1; DNA; Virus; Reverse transcriptase; Genetics; Genome; Gene; Polymerase chain reaction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002325329,0.0003530419,0.0002419385,0.0002094896,0.0001668181,0.0003331834,0.0002482571,0.0003743764,0.001720712],"category_scores_gemma":[0.0002870393,0.0002083429,0.0002520632,0.0001008988,0.0002588886,0.0001747137,0.0002917854,0.0006520216,0.0004775194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001915187,"about_ca_system_score_gemma":0.0001757556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002874432,"about_ca_topic_score_gemma":0.0003211256,"domain_scores_codex":[0.9998322,0.00003033713,0.0000222755,0.00003925927,0.00005005531,0.00002582802],"domain_scores_gemma":[0.9996642,0.0000843103,0.00009146953,0.00008308334,0.00002686426,0.00005010688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001780137,0.00001161038,0.0003062748,0.00001961562,0.000004611245,0.00003090152,0.00002152701,0.00003773762,0.9986672,0.000105998,0.00001818571,0.0007584634],"study_design_scores_gemma":[0.00001282201,0.0002768946,0.004455356,0.00001011953,0.0000166729,0.001054201,0.00003643279,0.0007024938,0.9914083,0.0001386951,0.001882839,0.000005201021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886521,0.001156351,0.008257416,0.00008848756,0.00002979047,0.00004996892,0.0002320738,0.0001455688,0.00138839],"genre_scores_gemma":[0.9918765,0.0003149697,0.00570023,0.00004024755,0.000008058934,0.00002832384,0.0004529957,0.00003177697,0.001546918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001720712,"threshold_uncertainty_score":0.005756378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005783585091958996,"score_gpt":0.2059835160776421,"score_spread":0.2001999309856831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}