{"id":"W2103702458","doi":"10.1046/j.0954-6820.2003.01256.x","title":"HDL deficiency and atherosclerosis: lessons from Tangier disease","year":2004,"lang":"en","type":"letter","venue":"Journal of Internal Medicine","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Tangier disease; ABCA1; Medicine; Internal medicine; Cholesterol; ATP Binding Cassette Transporter 1; Context (archaeology); Coronary artery disease; High-density lipoprotein; Endocrinology; Cardiology; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003821586,0.0004805526,0.00143076,0.0004796378,0.0000506585,0.00003808796,0.0003571562,0.0004004906,0.0005240999],"category_scores_gemma":[0.000572846,0.0002992625,0.0003766844,0.0001400392,0.0003685714,0.0001379747,0.00008655837,0.003069991,0.00002190966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001878,"about_ca_system_score_gemma":0.0003346994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002482011,"about_ca_topic_score_gemma":0.000004769247,"domain_scores_codex":[0.9967125,0.00008199302,0.001226111,0.0003709021,0.001215476,0.0003929913],"domain_scores_gemma":[0.9973782,0.0001868152,0.001062856,0.0004118272,0.0003660155,0.0005942796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008683347,0.0002293318,0.009071184,0.000541586,0.0006245537,0.006053702,0.001141366,0.000001968478,0.003064517,0.00003164335,0.9657279,0.01264394],"study_design_scores_gemma":[0.008184051,0.001171978,0.1489699,0.01980027,0.003139919,0.001895166,0.0001692105,0.000006444622,0.00008631392,0.001230449,0.8149838,0.0003624733],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1236491,0.02578775,0.0004973945,0.8451713,0.003998898,0.00020953,0.0000711317,0.00002189896,0.0005930747],"genre_scores_gemma":[0.1309066,0.004187316,0.0004161145,0.81222,0.0488796,0.000006221931,0.00004449394,0.0001262255,0.003213455],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.150744,"threshold_uncertainty_score":0.9999459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02835341537238561,"score_gpt":0.2961436899251809,"score_spread":0.2677902745527953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}