{"id":"W2103982975","doi":"10.1113/jphysiol.2012.234682","title":"Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle","year":2012,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Francis Xavier University; University of Guelph","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Phosphocreatine; Creatine; Creatine kinase; Skeletal muscle; Mitochondrion; Adenosine triphosphate; Biology; ATP–ADP translocase; Cytosol; Phosphate; Biochemistry; Internal medicine; Endocrinology; Inner mitochondrial membrane; Medicine; Enzyme; Energy metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002765071,0.0001167344,0.0002391228,0.00003842962,0.0000750499,0.000006182062,0.0001302653,0.0001131912,0.00001729678],"category_scores_gemma":[0.00003524417,0.00008267081,0.00006252609,0.00005990097,0.0001002228,0.00001705877,0.00006613265,0.0001627127,7.603738e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007147976,"about_ca_system_score_gemma":0.00001086945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003360932,"about_ca_topic_score_gemma":0.000005313169,"domain_scores_codex":[0.9991999,0.0001937726,0.0002126707,0.000101181,0.00007351104,0.0002189908],"domain_scores_gemma":[0.9994332,0.00001987519,0.0002682611,0.000151693,0.00005385574,0.0000731756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004473891,0.0001565771,0.0001606233,0.0000164974,0.00002014692,8.43649e-7,0.00006980815,0.00001352451,0.995672,0.000004961537,0.0009493608,0.002488226],"study_design_scores_gemma":[0.001854624,0.0002137863,0.2217418,0.00005572564,0.00006708268,0.00002224687,0.00005952831,0.00002022423,0.7735426,0.0001641398,0.00212702,0.0001311408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939311,0.005590597,0.00005286843,0.00008609556,0.0002200842,0.00009442245,0.00001040215,0.000002374979,0.00001211586],"genre_scores_gemma":[0.997676,0.00155201,0.00007769023,0.00004524989,0.0005834108,0.000002616454,0.00001652561,0.0000120108,0.00003448307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2221294,"threshold_uncertainty_score":0.3371218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008734484617821444,"score_gpt":0.2471893037792834,"score_spread":0.238454819161462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}