{"id":"W2104012489","doi":"10.1139/v05-211","title":"Dihydropyrimidinones containing boronic acids","year":2005,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Multicomponent Synthesis of Heterocycles","field":"Chemistry","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Biginelli reaction; Urea; Boronic acid; Ethyl acetoacetate; Lewis acids and bases; Combinatorial chemistry; Catalysis; Organic chemistry; Boron; Cancer cell lines; Thiourea; Cancer; Cancer cell","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001418086,0.0003827446,0.0002486486,0.0002710967,0.0001365288,0.0001422963,0.0003299208,0.0002832213,0.002152321],"category_scores_gemma":[0.0001465259,0.000149504,0.0001503903,0.0002445136,0.0001404863,0.0003664205,0.0002782693,0.0003258114,0.0006736192],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003008371,"about_ca_system_score_gemma":0.0001992916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000291342,"about_ca_topic_score_gemma":0.001094418,"domain_scores_codex":[0.9998937,0.00001509772,0.000007884921,0.00002190868,0.0000272344,0.00003424152],"domain_scores_gemma":[0.9999062,0.00001507857,0.00002324169,0.00001133655,0.00001511087,0.00002897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001232876,0.00003759361,0.00009246019,0.0001082877,0.000007043268,0.00009316503,0.00002771228,0.0002174638,0.9938917,0.0006723958,0.00008039519,0.004648502],"study_design_scores_gemma":[0.00003203709,0.0005784072,0.0004421999,0.000006847669,0.00000883432,0.0001821188,0.00001106446,0.000294155,0.9951171,0.0001022603,0.00321922,0.000005859574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9730695,0.002844305,0.008074124,0.00009145517,0.0000559178,0.0001386849,0.0003821109,0.0001532695,0.0151906],"genre_scores_gemma":[0.9877379,0.001702562,0.005753374,0.00006712425,0.00001291614,0.0000624109,0.0003127162,0.00002805704,0.00432289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002152321,"threshold_uncertainty_score":0.007200241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01472028621316974,"score_gpt":0.2260693178851992,"score_spread":0.2113490316720295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}