{"id":"W2104076405","doi":"10.1016/j.thromres.2004.02.015","title":"Heparin cofactor II is more sensitive than antithrombin to secretory impairment arising from mutations introduced into its carboxy-terminal region","year":2004,"lang":"en","type":"article","venue":"Thrombosis Research","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Canadian Blood Services","funders":"Canadian Blood Services","keywords":"Antithrombin; Heparin cofactor II; Heparin; Cofactor; Thrombin; Terminal (telecommunication); Biochemistry; Chemistry; Medicine; Platelet; Internal medicine; Enzyme; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002622106,0.0004546731,0.0004673372,0.0004142334,0.000224201,0.0005032708,0.0003576892,0.0006013701,0.002207635],"category_scores_gemma":[0.0006671472,0.0002182192,0.0004408022,0.0003031641,0.0006012967,0.0002445478,0.0003070737,0.0006695352,0.0006755064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002717708,"about_ca_system_score_gemma":0.0002482284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001443843,"about_ca_topic_score_gemma":0.000648702,"domain_scores_codex":[0.9996767,0.00006928137,0.00006301863,0.00006747714,0.00007109146,0.00005237438],"domain_scores_gemma":[0.9993135,0.0001642946,0.0001981252,0.00009686933,0.00008766818,0.0001395824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002563946,0.00002999632,0.00091741,0.00002311636,0.00002298669,0.0005440502,0.00003063372,0.00006043909,0.9970637,0.0001235588,0.00006469098,0.0008630857],"study_design_scores_gemma":[0.0000531208,0.000301648,0.0125076,0.000008054624,0.00006204684,0.005071123,0.00004477317,0.0007789888,0.9779342,0.00009538855,0.003127417,0.00001566927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963024,0.0004817497,0.001936612,0.00009725122,0.00007919432,0.000018342,0.000324273,0.00006662207,0.0006936329],"genre_scores_gemma":[0.9971586,0.0001586088,0.0007551959,0.00007034592,0.00002202192,0.00000977049,0.000515811,0.00004640491,0.001263271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002207635,"threshold_uncertainty_score":0.007385254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09878663481227808,"score_gpt":0.4010358754793248,"score_spread":0.3022492406670467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}