{"id":"W2104182629","doi":"10.1128/mcb.00357-06","title":"Association between SAP and FynT: Inducible SH3 Domain-Mediated Interaction Controlled by Engagement of the SLAM Receptor","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"National Cancer Institute; Canadian Institutes of Health Research; Centre National de la Recherche Scientifique","keywords":"SH3 domain; Biology; SH2 domain; Signal transducing adaptor protein; Cell biology; HAMP domain; Tyrosine phosphorylation; Phosphorylation; Tyrosine; Receptor; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Binding domain; Binding site; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012911,0.0002406908,0.0001671158,0.0001038249,0.0001221701,0.0001949339,0.0002293599,0.0002100434,0.0009433338],"category_scores_gemma":[0.0001114832,0.0001117598,0.0001963241,0.00009119844,0.0001315375,0.0001422314,0.0003919945,0.000363901,0.0003518302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002527127,"about_ca_system_score_gemma":0.0001298638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002404649,"about_ca_topic_score_gemma":0.0002568024,"domain_scores_codex":[0.9998172,0.00003391716,0.0000108481,0.00002975391,0.00003874599,0.00006956562],"domain_scores_gemma":[0.9999306,0.000009679165,0.00002019199,0.000008235811,0.000004839626,0.00002646698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001231231,0.00001872886,0.0001971746,0.0000185894,0.000003626987,0.0001039105,0.000007880833,0.00002056412,0.9989734,0.00007987084,0.00002681077,0.0004263596],"study_design_scores_gemma":[0.00003264034,0.0002329851,0.01133968,0.000004555075,0.00001315937,0.0006971934,0.00001863938,0.003328562,0.9821597,0.00006193155,0.002105511,0.000005543644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971538,0.0004489875,0.001629519,0.00002653416,0.00001341977,0.00001633547,0.00007873944,0.00002626848,0.0006063581],"genre_scores_gemma":[0.9974348,0.0001552556,0.0009914178,0.00002386904,0.000008395073,0.00002419743,0.0002146804,0.000005670172,0.001141648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009433338,"threshold_uncertainty_score":0.003155768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005078697352245268,"score_gpt":0.2030247232181046,"score_spread":0.1979460258658594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}