{"id":"W2104182629","doi":"10.1128/mcb.00357-06","title":"Association between SAP and FynT: Inducible SH3 Domain-Mediated Interaction Controlled by Engagement of the SLAM Receptor","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"National Cancer Institute; Canadian Institutes of Health Research; Centre National de la Recherche Scientifique","keywords":"SH3 domain; Biology; SH2 domain; Signal transducing adaptor protein; Cell biology; HAMP domain; Tyrosine phosphorylation; Phosphorylation; Tyrosine; Receptor; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Binding domain; Binding site; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004359726,0.0001452671,0.0003077816,0.00007243222,0.0001609759,0.00001293209,0.00007556595,0.0003238293,0.0002735669],"category_scores_gemma":[0.0001021426,0.0001077908,0.00009422684,0.00008577457,0.00010242,0.00004185093,0.00006761056,0.0003067132,0.00003564906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000534786,"about_ca_system_score_gemma":0.00001469253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002068657,"about_ca_topic_score_gemma":0.000007076153,"domain_scores_codex":[0.9985061,0.0006671176,0.0003543967,0.0002403904,0.00003298024,0.0001990468],"domain_scores_gemma":[0.9992947,0.0001741027,0.0003008429,0.000149642,0.0000688299,0.00001189052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001418539,0.00005587231,0.01081189,0.000007196586,0.0002692614,1.949087e-7,0.00006706207,6.401897e-7,0.9824916,0.0003821612,0.005260526,0.0005117931],"study_design_scores_gemma":[0.002951867,0.000185892,0.002005539,0.00001241446,0.0001081048,0.000003131306,0.000146178,0.000003178319,0.840513,0.000202834,0.1537503,0.0001175777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923015,0.002992908,0.001014263,0.0006464989,0.001168735,0.0003307934,0.00001842617,0.00002269306,0.001504171],"genre_scores_gemma":[0.9958236,0.0000791994,0.00001521146,0.0001547089,0.00002987512,0.00002218948,0.0005906394,0.00001035656,0.003274216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1484898,"threshold_uncertainty_score":0.4395581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005078697352245268,"score_gpt":0.2030247232181046,"score_spread":0.1979460258658594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}