{"id":"W2104191615","doi":"10.1074/jbc.m203285200","title":"Congenital Disorders of Glycosylation Type Ig Is Defined by a Deficiency in Dolichyl-P-mannose:Man7GlcNAc2-PP-dolichyl Mannosyltransferase","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Merck Canada","keywords":"Dolichol; Glycosylation; Glycoprotein; Mannose; Biology; Endoplasmic reticulum; Gene; Phenotype; Biochemistry; Molecular biology; Biosynthesis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006378168,0.0009411609,0.0002336218,0.0005782836,0.0002462007,0.0002904656,0.0002326859,0.0004923727,0.0014131],"category_scores_gemma":[0.0002150919,0.0001051376,0.0001650384,0.0006080551,0.0007711264,0.0001390736,0.0003348138,0.0002995572,0.0002928106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003159202,"about_ca_system_score_gemma":0.0003284556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002113325,"about_ca_topic_score_gemma":0.001730404,"domain_scores_codex":[0.9998624,0.00001279004,0.0000132105,0.00004633554,0.00002937423,0.00003585632],"domain_scores_gemma":[0.9998888,0.00001301595,0.00004456528,0.000006544057,0.000007407238,0.00003972467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008517806,0.0001273726,0.080506,0.0003949291,0.0000956503,0.08268973,0.0007410046,0.0004415673,0.7426881,0.006759417,0.002611771,0.08209267],"study_design_scores_gemma":[0.0001372678,0.001122557,0.2917708,0.0001245949,0.0001484185,0.4817089,0.0005128675,0.001630233,0.163813,0.002455325,0.05652142,0.00005460829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874078,0.004538533,0.002790274,0.0001905792,0.00006131631,0.00003956674,0.0006492861,0.0002732677,0.00404944],"genre_scores_gemma":[0.9932481,0.001926924,0.002434046,0.00007044788,0.00003781957,0.00001484324,0.0005142789,0.00002624704,0.001727357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002113325,"threshold_uncertainty_score":0.004727304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02019444034973492,"score_gpt":0.2633331177492969,"score_spread":0.2431386773995619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}