{"id":"W2104238967","doi":"10.1136/thoraxjnl-2011-201321","title":"Serum levels and genotype distribution of α <sub>1</sub> -antitrypsin in the general population","year":2012,"lang":"en","type":"article","venue":"Thorax","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital Foundation","funders":"Abbott Diagnostics; Lungenliga Schweiz; Bundesamt für Gesundheit; European Commission; Chinese Society of Clinical Oncology; Wellcome Trust; Freiwillige Akademische Gesellschaft; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Fondazione Cariplo; National Science Foundation","keywords":"Medicine; Cohort; Percentile; COPD; Population; Genotype; Internal medicine; Gastroenterology; Immunology; Environmental health; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002679346,0.00006303367,0.00006469739,0.0000127172,0.00003192262,0.000006413457,0.0000533929,0.00008029913,0.00000254303],"category_scores_gemma":[0.00002246221,0.00004849955,0.00002298656,0.00005509598,0.00001764971,0.000006894719,0.00003517383,0.00004297505,0.000002286314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007571065,"about_ca_system_score_gemma":0.00001014374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003087624,"about_ca_topic_score_gemma":0.0000135177,"domain_scores_codex":[0.9995251,0.00007051204,0.0001071557,0.00009136693,0.00007000827,0.0001358244],"domain_scores_gemma":[0.9997773,0.000002964914,0.00004325061,0.0001339427,0.00001777118,0.00002483499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001840923,0.00002529349,0.007481005,0.000008365069,0.000004153477,2.413859e-7,0.00003455326,0.000002959057,0.9877285,0.001183622,0.0001283668,0.003384482],"study_design_scores_gemma":[0.0001149643,0.00005024977,0.1744019,0.000005375957,0.000006010822,0.000004996702,0.00001975905,0.00002569657,0.8246529,0.0003394418,0.0003222126,0.0000565096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979481,0.0007692035,0.0008968617,0.00005061218,0.00007656604,0.0001215223,0.00005128844,0.000002886856,0.00008303361],"genre_scores_gemma":[0.9993913,0.00002944271,0.0001196316,0.00007056621,0.0002061544,0.000006143857,0.0001595403,0.000005551583,0.00001171571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1669209,"threshold_uncertainty_score":0.1977754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01528335809435523,"score_gpt":0.2608986667737735,"score_spread":0.2456153086794182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}