{"id":"W2104243677","doi":"10.1186/1475-2840-13-105","title":"Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β–dependent vascular endothelial cadherin tyrosine phosphorylation","year":2014,"lang":"en","type":"article","venue":"Cardiovascular Diabetology","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; Texas Heart Institute","keywords":"Adherens junction; VE-cadherin; Medicine; Phosphorylation; Angiology; Cadherin; Tyrosine phosphorylation; Cell biology; Receptor tyrosine kinase; Tyrosine kinase; Internal medicine; Biochemistry; Biology; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005265987,0.0004291708,0.001013508,0.0001471878,0.0003147445,0.00003592796,0.0002980175,0.0003428495,0.0002583369],"category_scores_gemma":[0.0009665359,0.0004000508,0.000745323,0.0004263712,0.0004442111,0.0001871123,0.0001270773,0.0003527263,0.0001180091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009001717,"about_ca_system_score_gemma":0.00004682696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003112308,"about_ca_topic_score_gemma":0.00001429992,"domain_scores_codex":[0.9963394,0.0007509146,0.0006080809,0.000969203,0.000760523,0.0005718379],"domain_scores_gemma":[0.9982538,0.0001973037,0.0002565121,0.0009344977,0.0001807267,0.0001771494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000896514,0.0001170246,0.0006956676,0.00005318354,0.0005889186,0.000006207705,0.0001841641,0.00007814891,0.9864736,0.0007122419,0.002676009,0.008325187],"study_design_scores_gemma":[0.0026398,0.0002075679,0.0009067603,0.00001459156,0.0003674196,0.00001578498,0.00003722828,0.0001296384,0.8479957,0.0003221894,0.1469975,0.0003658053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9723688,0.004517599,0.01780228,0.0002009058,0.002182086,0.001033831,0.001253207,0.0002074606,0.0004338052],"genre_scores_gemma":[0.9979433,0.0005541618,0.0000919688,0.0003236974,0.0002479821,0.0002955649,0.0001354565,0.0000625363,0.0003453043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1443215,"threshold_uncertainty_score":0.9998451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00987168325625675,"score_gpt":0.2105883894377581,"score_spread":0.2007167061815013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}