{"id":"W2104278151","doi":"10.3389/fgene.2013.00045","title":"Reading, writing, and repair: the role of ubiquitin and the ubiquitin-like proteins in DNA damage signaling and repair","year":2013,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Terry Fox Foundation; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Chromatin; DNA repair; DNA damage; Cell biology; Biology; Histone; Chromatin remodeling; Ubiquitin; SUMO protein; Genome instability; Histone-modifying enzymes; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009543526,0.0002037459,0.0002702328,0.00007148757,0.0001130154,0.00004893171,0.0001863573,0.00018274,0.000006947949],"category_scores_gemma":[0.0001466204,0.0001480044,0.00006790605,0.0001107953,0.0005944574,0.000008363128,0.0002948637,0.0002145497,4.55833e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001097473,"about_ca_system_score_gemma":0.00004236804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001372357,"about_ca_topic_score_gemma":0.00006205119,"domain_scores_codex":[0.9984353,0.0002825435,0.0004139082,0.0004049343,0.0001385555,0.0003247542],"domain_scores_gemma":[0.9992664,0.00005218164,0.0001473504,0.0004023451,0.00005976997,0.00007196226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005547813,0.000148667,0.4698212,0.0005251117,0.0002171092,0.00001456377,0.006253971,0.00007670734,0.4923824,0.001528904,0.003890532,0.024586],"study_design_scores_gemma":[0.005953555,0.001030849,0.0626997,0.0004800747,0.0001361067,0.00008255083,0.01572214,0.02009025,0.8404489,0.01346168,0.03880166,0.001092544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982677,0.01473924,0.0001727849,0.0001992681,0.00007041809,0.001058983,0.00001295183,0.00001939977,0.001049988],"genre_scores_gemma":[0.9853706,0.002082432,0.01178714,0.0002588938,0.0001046389,0.0001633404,0.000011956,0.00002982298,0.0001912249],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4071215,"threshold_uncertainty_score":0.6035447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005061971975228358,"score_gpt":0.2040413914560238,"score_spread":0.1989794194807954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}