{"id":"W2104327327","doi":"10.1128/iai.00406-12","title":"Mycobacterium avium subsp. paratuberculosis Inhibits Gamma Interferon-Induced Signaling in Bovine Monocytes: Insights into the Cellular Mechanisms of Johne's Disease","year":2012,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Beef Cattle Research Council; Ministry of Agriculture - Saskatchewan","keywords":"Paratuberculosis; Biology; Kinome; Microbiology; Immune system; Mycobacterium; Interferon gamma; Interferon; Signal transduction; Virology; Immunology; Cell biology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001568283,0.0001913868,0.000240857,0.0001072096,0.0001450587,0.0002848806,0.0001002005,0.0002477903,0.0008544379],"category_scores_gemma":[0.0001009126,0.00008801835,0.0001811179,0.0001074091,0.0001045856,0.0001060861,0.0001217474,0.0003240359,0.0003402678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002205109,"about_ca_system_score_gemma":0.0002141361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008028514,"about_ca_topic_score_gemma":0.001744237,"domain_scores_codex":[0.9998645,0.00003126713,0.000008883571,0.00001503598,0.00002242804,0.00005789398],"domain_scores_gemma":[0.9999547,0.00001175076,0.000008532537,0.000005417712,0.000007581899,0.00001190534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002636575,0.00002890934,0.0003881982,0.00004773713,0.000002598525,0.00003836902,0.00002585923,0.00003320784,0.9976267,0.00002607766,0.0000325756,0.001486084],"study_design_scores_gemma":[0.00007344509,0.001315422,0.07335883,0.0000356633,0.00003840649,0.0004957771,0.0002793992,0.002330591,0.9160095,0.0001857598,0.005865463,0.00001159652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920632,0.005224094,0.001114487,0.0002091509,0.00002971475,0.00001647294,0.0002378823,0.00002504107,0.001080017],"genre_scores_gemma":[0.9966218,0.001610994,0.0006102524,0.0001045826,0.00001176521,0.00002453205,0.0002078628,0.000004699572,0.0008034426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008544379,"threshold_uncertainty_score":0.002858341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02502048119717841,"score_gpt":0.2776423226230811,"score_spread":0.2526218414259027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}