{"id":"W2104327327","doi":"10.1128/iai.00406-12","title":"Mycobacterium avium subsp. paratuberculosis Inhibits Gamma Interferon-Induced Signaling in Bovine Monocytes: Insights into the Cellular Mechanisms of Johne's Disease","year":2012,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Beef Cattle Research Council; Ministry of Agriculture - Saskatchewan","keywords":"Paratuberculosis; Biology; Kinome; Microbiology; Immune system; Mycobacterium; Interferon gamma; Interferon; Signal transduction; Virology; Immunology; Cell biology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004617706,0.0002132317,0.0003268624,0.0002554534,0.0001664544,0.00003768063,0.00009324071,0.0001322498,0.0001560372],"category_scores_gemma":[0.0003843419,0.0001549907,0.0001339347,0.0004758322,0.00008435987,0.0003776589,0.0002036883,0.0004922207,0.0000176289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001369562,"about_ca_system_score_gemma":0.0000962707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002653237,"about_ca_topic_score_gemma":0.0001890461,"domain_scores_codex":[0.9984145,0.0003922837,0.0003890122,0.0001919784,0.0002579053,0.0003542849],"domain_scores_gemma":[0.9987942,0.0001321869,0.0001194062,0.0004360302,0.000148589,0.0003695963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004995535,0.000599522,0.3110601,0.0002599992,0.0000465322,0.000003285354,0.001551272,0.000001190746,0.6848443,0.0001929392,0.00003445254,0.000906849],"study_design_scores_gemma":[0.0007945204,0.0003566105,0.4708424,0.0002739002,0.00006443079,0.000003889709,0.0001516614,0.00006468299,0.5267638,0.0002528357,0.0003054329,0.0001258411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997624,0.0007577458,0.0001746165,0.0002639259,0.0003811769,0.0004873165,0.000004127975,0.00003667642,0.0002704346],"genre_scores_gemma":[0.9990234,0.0004861151,0.00003401496,0.0001895072,0.0001118486,0.00006388895,0.00002952857,0.00002152771,0.0000401835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1597823,"threshold_uncertainty_score":0.6320338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02502048119717841,"score_gpt":0.2776423226230811,"score_spread":0.2526218414259027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}