{"id":"W2104332452","doi":"10.1039/c0mt00031k","title":"The puzzle posed by COMMD1, a newly discovered protein binding Cu(<scp>ii</scp>)","year":2010,"lang":"en","type":"article","venue":"Metallomics","topic":"Trace Elements in Health","field":"Nursing","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children; Canadian Liver Foundation; Canadian Association for the Study of the Liver","keywords":"ATP7A; Menkes disease; Copper; Wilson's disease; Intracellular; ATPase; Extracellular; Biochemistry; Biology; Copper metabolism; Hepatocyte; Homeostasis; Chemistry; Cell biology; Internal medicine; Disease; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.001134521,0.000325291,0.0003395503,0.0000895176,0.001488457,0.0003095201,0.0008300117,0.0002050095,0.0000172296],"category_scores_gemma":[0.000912226,0.0002529816,0.0001496852,0.000308105,0.0002056131,0.0003289351,0.0002216899,0.001033864,0.0001134111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001623806,"about_ca_system_score_gemma":0.00007213707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002700968,"about_ca_topic_score_gemma":0.001408664,"domain_scores_codex":[0.9973561,0.0002055288,0.0005772279,0.0004543406,0.0004974814,0.0009093598],"domain_scores_gemma":[0.9979154,0.0005328826,0.0003471202,0.0009330827,0.00006340392,0.0002080607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001002108,0.0003541368,0.001980076,0.00005944559,0.0001148143,0.000004304446,0.001647117,0.00001194688,0.9601129,0.00272048,0.02310196,0.009792653],"study_design_scores_gemma":[0.002011696,0.0003682296,0.0009975567,0.00004671814,0.00009559343,0.00001507613,0.0009377005,0.0009203556,0.2703291,0.00201232,0.7220046,0.0002610629],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893567,0.0002133358,0.0001485017,0.003809457,0.003110615,0.001419309,0.0001403138,0.0001653874,0.001636381],"genre_scores_gemma":[0.9868394,0.0000183206,0.006013703,0.0005166352,0.0003694684,0.0001247337,0.00008921739,0.0001234522,0.005905066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6989027,"threshold_uncertainty_score":0.9999923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0126591385322631,"score_gpt":0.2702251148060512,"score_spread":0.2575659762737881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}