{"id":"W2104368843","doi":"10.1038/emboj.2009.193","title":"MRE11–RAD50–NBS1 is a critical regulator of FANCD2 stability and function during DNA double‐strand break repair","year":2009,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Fonds Québécois de la Recherche sur la Nature et les Technologies; Novartis Foundation; Fanconi Anemia Research Fund; National Cancer Institute; National Science Foundation","keywords":"Research center; Library science; Biology; Computer science; Political science; Law","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006056003,0.0001362023,0.0001692594,0.00002804208,0.0001779319,0.00003389901,0.0001303202,0.0001043164,0.00008986091],"category_scores_gemma":[0.00007840724,0.0001000812,0.0001569026,0.0000570641,0.0001201823,0.00001159195,0.000048518,0.0001903346,0.000001500405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001765795,"about_ca_system_score_gemma":0.00005311842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003354706,"about_ca_topic_score_gemma":0.000003608523,"domain_scores_codex":[0.9989249,0.00009786025,0.0003015237,0.0002333528,0.0002061912,0.0002362019],"domain_scores_gemma":[0.9992566,0.00001670176,0.00009729015,0.0003630492,0.0001415947,0.0001247355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009030831,0.00007909943,0.0004472433,0.00003023274,0.00006099474,0.00000676898,0.0001661753,0.000004834836,0.996525,0.0004931249,0.0005772723,0.0007061595],"study_design_scores_gemma":[0.001352969,0.0006024792,0.01647833,0.0000369049,0.00008425851,0.001035193,0.0002180925,0.0001039622,0.9752018,0.003717391,0.001012442,0.000156113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965756,0.0006463426,0.0006409174,0.001102306,0.0001377093,0.0001121993,0.00000718961,0.00001857632,0.0007591376],"genre_scores_gemma":[0.9988014,0.00007965687,0.0004115076,0.000182869,0.0003175628,0.000001916437,0.000002050465,0.00001044041,0.0001926188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02132315,"threshold_uncertainty_score":0.4081191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01106842230147157,"score_gpt":0.2490815189146258,"score_spread":0.2380130966131543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}