{"id":"W2104407980","doi":"10.1128/mcb.00686-07","title":"Elevated Expression of DecR1 Impairs ErbB2/Neu-Induced Mammary Tumor Development","year":2007,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre for Advancing Health Outcomes; University of British Columbia; McGill University","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"Biology; Carcinogenesis; Mammary tumor; Ectopic expression; HER2/neu; Oncogene; Cancer research; Cancer; Cell growth; Downregulation and upregulation; Cancer cell; Breast cancer; Apoptosis; Endocrinology; Cell culture; Cell cycle; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004216931,0.000250058,0.0003070554,0.0001064845,0.00007626435,0.000009709819,0.0002243914,0.0002715427,0.00001319815],"category_scores_gemma":[0.00004950436,0.0002296886,0.0001162564,0.0001164938,0.0001035717,0.000004040596,0.0002205297,0.0001165375,0.000002830912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001269101,"about_ca_system_score_gemma":0.0001387666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002737416,"about_ca_topic_score_gemma":0.00001501951,"domain_scores_codex":[0.9984467,0.00009493391,0.0004114393,0.0005019716,0.000109482,0.0004354864],"domain_scores_gemma":[0.9991713,0.00001179094,0.0001465377,0.0004018859,0.00009755836,0.0001709969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001300089,0.00006655263,0.0007024336,0.00002995421,0.0000483941,0.000003589125,0.00005755101,0.000001257538,0.9932745,0.0003879273,0.0002625819,0.005035312],"study_design_scores_gemma":[0.0007284366,0.0002094921,0.001249339,0.00001425532,0.00001876063,0.00002704929,0.00004533375,0.000003947669,0.8981907,0.0001087985,0.09915251,0.0002514244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9397282,0.004546076,0.05395215,0.00002504146,0.001115084,0.0002071971,0.000006124629,0.00001861291,0.0004015018],"genre_scores_gemma":[0.9945869,0.0001155484,0.004002446,0.0002853744,0.0006820484,0.00001576936,0.0001752155,0.00002893669,0.0001077721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09888992,"threshold_uncertainty_score":0.9366428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0067682342022477,"score_gpt":0.2309082612373147,"score_spread":0.224140027035067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}