{"id":"W2104459135","doi":"10.1074/jbc.m605880200","title":"Toward Elucidating the Membrane Topology of Helix Two of the Colicin E1 Channel Domain","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Institute of General Medical Sciences","keywords":"Colicin; Helix (gastropod); Lipid bilayer; Crystallography; Chemistry; Bilayer; Membrane; Fluorescence anisotropy; Biophysics; Fluorophore; Fluorescence; Biology; Biochemistry; Escherichia coli; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001531583,0.0001821885,0.0001328188,0.0001492011,0.0002274531,0.0003369201,0.000248967,0.0002811521,0.0009530758],"category_scores_gemma":[0.0003106292,0.0001024238,0.0001313799,0.0001375807,0.0001937567,0.0005184833,0.0001636086,0.0008192089,0.0002071204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004823648,"about_ca_system_score_gemma":0.0002595321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008224302,"about_ca_topic_score_gemma":0.001073237,"domain_scores_codex":[0.9999502,0.00001055603,0.000002495012,0.00001023759,0.00001408528,0.00001244144],"domain_scores_gemma":[0.9998686,0.00003353787,0.0000244484,0.000009025975,0.00003445121,0.00002988273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001086311,0.00002962031,0.0003843737,0.00004046895,0.000002129971,0.00005526999,0.00005357625,0.0004406999,0.9965996,0.001060023,0.00003934579,0.001186198],"study_design_scores_gemma":[0.00001900358,0.0001397689,0.004327398,0.0000256939,0.000008751644,0.0002277273,0.0001839751,0.0128578,0.9767651,0.0006424673,0.004790032,0.00001231043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877412,0.0003748754,0.01000567,0.0001442229,0.000020263,0.00002941192,0.0001645992,0.0000307818,0.001489046],"genre_scores_gemma":[0.9906613,0.0003534817,0.00669598,0.00007403049,0.00000369247,0.00001874826,0.0006064364,0.00001121463,0.00157508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009530758,"threshold_uncertainty_score":0.003499806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01517556279156549,"score_gpt":0.256025182055345,"score_spread":0.2408496192637795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}