{"id":"W2104475366","doi":"10.1111/j.1462-5822.2005.00582.x","title":"Leishmania donovani promastigotes induce periphagosomal F-actin accumulation through retention of the GTPase Cdc42","year":2005,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; Armand-Frappier Foundation; McGill University","keywords":"Phagosome; RHOA; Lipophosphoglycan; Biology; Leishmania donovani; Cell biology; Internalization; CDC42; Actin; GTPase; Myosin; RAC1; Phagocytosis; Biochemistry; Immunology; Signal transduction; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001225908,0.0003857305,0.0002379445,0.0002192902,0.0001737168,0.0003151345,0.00015055,0.0002592915,0.0007601123],"category_scores_gemma":[0.0001000093,0.0001816585,0.000214651,0.00007689228,0.0002335864,0.0001122903,0.0002380963,0.0004261445,0.0003433237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002516345,"about_ca_system_score_gemma":0.0002086707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005429374,"about_ca_topic_score_gemma":0.0008677755,"domain_scores_codex":[0.9998587,0.00002566297,0.000008629389,0.00001811215,0.00003315585,0.00005580341],"domain_scores_gemma":[0.9999207,0.00001251232,0.00001925655,0.00001033258,0.00001608317,0.00002100894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004084301,0.00002168784,0.0000705453,0.00002690837,0.000001740455,0.00003145502,0.000008687981,0.00001689584,0.9993986,0.00005462585,0.00001752871,0.0003104639],"study_design_scores_gemma":[0.00003253732,0.0002426864,0.006551037,0.00001078499,0.000008029509,0.0002289901,0.00003878186,0.0007870996,0.9895121,0.00004852372,0.00253572,0.000003588694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995509,0.001221703,0.0009294617,0.0000971913,0.00001126027,0.0000230313,0.0001028821,0.00006407499,0.00204128],"genre_scores_gemma":[0.9960467,0.0007106591,0.0008498494,0.00006646538,0.000005147194,0.0000392652,0.0002297987,0.0000166107,0.002035483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007601123,"threshold_uncertainty_score":0.002542794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02921175322198552,"score_gpt":0.2481757147537356,"score_spread":0.2189639615317501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}