{"id":"W2104503053","doi":"10.1038/onc.2010.612","title":"Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma","year":2011,"lang":"en","type":"article","venue":"Oncogene","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":274,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Cancer Research; Centre Hospitalier Universitaire de Nice; Institut National Du Cancer; Ligue Contre le Cancer; Agence Nationale de la Recherche","keywords":"Microphthalmia-associated transcription factor; Biology; Genetics; Transcription factor; Mitosis; Melanoma; Chromatin immunoprecipitation; Licensing factor; Cancer research; Cell biology; DNA replication; Gene; Control of chromosome duplication; Gene expression; Promoter","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001108952,0.0003266409,0.000175143,0.0005397221,0.0004074653,0.0002989008,0.0002718059,0.0002896117,0.001284939],"category_scores_gemma":[0.0001994085,0.0001824753,0.0001774128,0.0001400456,0.0002857829,0.0003897485,0.0002808687,0.0003360582,0.0003556272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007032382,"about_ca_system_score_gemma":0.0002636616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001516939,"about_ca_topic_score_gemma":0.001679356,"domain_scores_codex":[0.9999319,0.0000133084,0.000008231205,0.00001520087,0.00001562077,0.00001577266],"domain_scores_gemma":[0.999837,0.00004929841,0.00003019457,0.00002683157,0.0000142776,0.0000423675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000320407,0.00001589516,0.0003837898,0.00003135603,0.000003426841,0.0002418271,0.00002582812,0.00007540624,0.9961965,0.00111611,0.00007642853,0.001512965],"study_design_scores_gemma":[0.00001814202,0.00009475951,0.01174787,0.000008939754,0.00001212646,0.000649617,0.00003992072,0.001031218,0.9829649,0.0005183779,0.002907023,0.000007120491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842219,0.008098,0.003781548,0.0002683869,0.00006333558,0.00002093344,0.0005196146,0.0001841455,0.002842212],"genre_scores_gemma":[0.9960386,0.0006537074,0.0009620871,0.00002176439,0.00001320129,0.00001261759,0.000281678,0.00001750937,0.001998766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001516939,"threshold_uncertainty_score":0.005102456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02258012537723678,"score_gpt":0.2528859474998503,"score_spread":0.2303058221226135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}