{"id":"W2104528385","doi":"10.1124/dmd.32.2.212","title":"STEREOSELECTIVE PHARMACOKINETICS OF FLUOXETINE AND NORFLUOXETINE ENANTIOMERS IN PREGNANT SHEEP","year":2004,"lang":"en","type":"article","venue":"Drug Metabolism and Disposition","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"","keywords":"Fetus; Pharmacokinetics; Chemistry; Metabolite; Volume of distribution; Stereoselectivity; Urine; Internal medicine; Free fraction; Endocrinology; Pregnancy; Medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006490608,0.0003188649,0.0005086031,0.0003662959,0.0001393347,0.0000236677,0.0001468417,0.0001657146,0.00009290172],"category_scores_gemma":[0.00003774916,0.0003031018,0.00007532805,0.0004537968,0.0003113126,0.0002024666,0.0001221536,0.0004506299,0.000007142618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002426819,"about_ca_system_score_gemma":0.00005911424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001244326,"about_ca_topic_score_gemma":0.00002758443,"domain_scores_codex":[0.9980003,0.0003024929,0.0005633557,0.0004625359,0.0002065437,0.0004648109],"domain_scores_gemma":[0.9991205,0.0001135942,0.000203655,0.0001472283,0.0001187988,0.0002962143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001338077,0.001406893,0.008154114,0.0003444887,0.000239317,0.00006890118,0.006366135,0.001434437,0.8530361,0.01150371,0.0001355041,0.1159723],"study_design_scores_gemma":[0.01996305,0.0001451345,0.1420131,0.000185137,0.001033786,0.00008562524,0.0005946284,0.002152652,0.8040319,0.006409668,0.02246023,0.0009250602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757544,0.02097093,0.0002120042,0.0006061837,0.0006015669,0.0005442426,0.0001837155,0.00003559166,0.001091372],"genre_scores_gemma":[0.9862584,0.01215572,0.0005660692,0.0006122945,0.0001882668,0.00005099276,0.00005877614,0.0000305937,0.0000788563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.133859,"threshold_uncertainty_score":0.9999421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02884711373874646,"score_gpt":0.355603129736175,"score_spread":0.3267560159974285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}