{"id":"W2104531065","doi":"10.1101/gad.935901","title":"Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain","year":2001,"lang":"en","type":"article","venue":"Genes & Development","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":421,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; National Institute of General Medical Sciences; Seoul National University; Leukemia and Lymphoma Society","keywords":"RNA polymerase II; Biology; Transcription factor II D; RNA polymerase II holoenzyme; Transcription factor II E; Transcription factor II F; Molecular biology; Transcription factor II B; Transcription (linguistics); Transcription factor II H; Phosphorylation; General transcription factor; RNA polymerase; Cell biology; Promoter; RNA; Biochemistry; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002086132,0.0006034767,0.0003510003,0.0001822418,0.0001473438,0.0004671857,0.0002311315,0.0002729053,0.001562102],"category_scores_gemma":[0.0002915054,0.0002736209,0.0001987801,0.0001147243,0.0004226966,0.0002900599,0.0003669245,0.0005488468,0.0002504526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004449901,"about_ca_system_score_gemma":0.0003022835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005472943,"about_ca_topic_score_gemma":0.0007807892,"domain_scores_codex":[0.9997659,0.00003801797,0.00001374741,0.00004574206,0.00003899217,0.00009768381],"domain_scores_gemma":[0.9997883,0.00004787,0.00004389729,0.00001294068,0.00001263284,0.00009432192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001685396,0.0000588695,0.0004599669,0.00008376129,0.00001238954,0.0000810184,0.00001340917,0.0001876956,0.9949994,0.000255293,0.00004870921,0.002114126],"study_design_scores_gemma":[0.0001093348,0.0006221645,0.006962074,0.000009121976,0.00003131575,0.0003269562,0.00002961265,0.001459616,0.9892381,0.0001167915,0.001086773,0.000008093981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954624,0.00262672,0.0004832897,0.0000773782,0.00003866334,0.00001209998,0.0001078068,0.00001889022,0.001172803],"genre_scores_gemma":[0.9965514,0.001214244,0.0005478518,0.00005766694,0.00001544274,0.00002030743,0.0001743933,0.00001003111,0.001408643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001562102,"threshold_uncertainty_score":0.005225718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003451949376164284,"score_gpt":0.1959647229403865,"score_spread":0.1925127735642222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}