{"id":"W2104630973","doi":"10.1110/ps.0226203","title":"Protein conformational changes studied by diffusion NMR spectroscopy: Application to helix‐loop‐helix calcium binding proteins","year":2003,"lang":"en","type":"article","venue":"Protein Science","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; University of Calgary","keywords":"Helix (gastropod); Nuclear magnetic resonance spectroscopy; Calcium-binding protein; Chemistry; Crystallography; Calcium; Protein structure; Biophysics; Alpha helix; Circular dichroism; Stereochemistry; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003079103,0.0003854811,0.0002753177,0.0001892453,0.0002157158,0.0002155781,0.0002714495,0.0005011263,0.0003458996],"category_scores_gemma":[0.0004124046,0.0001403832,0.000142443,0.0001932725,0.0003416722,0.0003452112,0.000242546,0.000502637,0.0001159678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002708867,"about_ca_system_score_gemma":0.0001693024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007712053,"about_ca_topic_score_gemma":0.0006345426,"domain_scores_codex":[0.9999057,0.00002249048,0.000004273595,0.00003097471,0.00002226164,0.00001418768],"domain_scores_gemma":[0.9998338,0.00006398184,0.00002634234,0.00001575006,0.00003069888,0.00002928551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001993981,0.000007562196,0.00009021717,0.00002335726,0.000001785939,0.00001156882,0.0000143787,0.0001450948,0.9986542,0.0000401561,0.0000131386,0.0009785569],"study_design_scores_gemma":[0.00001822375,0.0002034481,0.003083866,0.000007507367,0.00000964927,0.0002216559,0.0000332518,0.01140857,0.9831995,0.0001790663,0.001622541,0.00001278606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9420713,0.002423774,0.05330716,0.0002938574,0.00003411796,0.0000945816,0.0002048232,0.0002204684,0.001349836],"genre_scores_gemma":[0.9511064,0.002727027,0.04487041,0.000114739,0.00002019183,0.0001036388,0.0001573352,0.0000393461,0.0008608474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007712053,"threshold_uncertainty_score":0.001965463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00861755630549367,"score_gpt":0.2676709572569476,"score_spread":0.2590534009514539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}