{"id":"W2104631267","doi":"10.1002/mrm.20074","title":"In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: Illustration of targeted delivery","year":2004,"lang":"en","type":"article","venue":"Magnetic Resonance in Medicine","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; U.S. Public Health Service","keywords":"Liposome; In vivo; Drug delivery; Pharmacokinetics; Drug; Doxorubicin; Distribution (mathematics); Chemistry; In vitro; Pharmacology; Targeted drug delivery; Biomedical engineering; Medicine; Chemotherapy; Surgery; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006898234,0.0001619108,0.0004966873,0.0002966159,0.00001550802,0.000003306163,0.0002597313,0.00006458681,0.0003241593],"category_scores_gemma":[0.0001782968,0.0001540635,0.00002577593,0.0007609383,0.0003846542,0.000170679,0.00005452632,0.000121434,0.000002591291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067964,"about_ca_system_score_gemma":0.0001194505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002367033,"about_ca_topic_score_gemma":0.00007035515,"domain_scores_codex":[0.9977301,0.0001085902,0.001036686,0.0002696338,0.0005632111,0.0002917872],"domain_scores_gemma":[0.9990092,0.0001446478,0.0003158307,0.0002903707,0.0001824917,0.00005744171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001470391,0.000162561,0.007894718,0.0001943561,0.000001183869,0.0000369498,0.00120137,0.01640725,0.9722179,0.00003333676,0.00003872601,0.001664569],"study_design_scores_gemma":[0.002630793,0.0003713622,0.00877498,0.001068732,0.00002383068,0.000004835148,0.0003408871,0.001531018,0.9848313,0.0001716322,0.0001337109,0.0001169698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884824,0.01030235,0.0001099561,0.0002355065,0.0004641154,0.0003393352,0.00001415282,0.00001051023,0.00004165451],"genre_scores_gemma":[0.9920269,0.0005885072,0.007168919,0.00002834864,0.0001242885,0.000008955399,9.373556e-7,0.00001611416,0.00003703353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01487623,"threshold_uncertainty_score":0.6282527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02098082468009903,"score_gpt":0.2849897407247871,"score_spread":0.2640089160446881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}