{"id":"W2104631267","doi":"10.1002/mrm.20074","title":"In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: Illustration of targeted delivery","year":2004,"lang":"en","type":"article","venue":"Magnetic Resonance in Medicine","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; U.S. Public Health Service","keywords":"Liposome; In vivo; Drug delivery; Pharmacokinetics; Drug; Doxorubicin; Distribution (mathematics); Chemistry; In vitro; Pharmacology; Targeted drug delivery; Biomedical engineering; Medicine; Chemotherapy; Surgery; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000266517,0.0004187707,0.0002478628,0.0002207212,0.0001233465,0.0002190975,0.0002942625,0.0005211681,0.000797946],"category_scores_gemma":[0.0003085104,0.0001611114,0.0001434183,0.0001127203,0.0002813256,0.0004817884,0.0002389428,0.0004365693,0.0003032803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002044923,"about_ca_system_score_gemma":0.0001767335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003554259,"about_ca_topic_score_gemma":0.0003121851,"domain_scores_codex":[0.9999058,0.00003242639,0.000005295749,0.00002277805,0.00001680737,0.00001695199],"domain_scores_gemma":[0.9998859,0.00004015053,0.00003484202,0.00001085169,0.0000174531,0.00001085872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000627325,0.00001150528,0.00005290865,0.00002253905,0.000001278591,0.00002662805,0.00000640303,0.00008242155,0.9985031,0.00005927104,0.00001408329,0.00115712],"study_design_scores_gemma":[0.000008969507,0.0002816272,0.0003858006,0.000003510791,0.000009738361,0.0001598636,0.00000840579,0.001839164,0.9962368,0.00005872737,0.00100281,0.000004582518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8798751,0.006284454,0.1096533,0.0004877779,0.0001118621,0.0001873459,0.0001919856,0.0004565861,0.002751603],"genre_scores_gemma":[0.9351377,0.003032443,0.05897614,0.0001418796,0.00003944583,0.0001425052,0.0001236041,0.00007205125,0.002334185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000797946,"threshold_uncertainty_score":0.002669454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02098082468009903,"score_gpt":0.2849897407247871,"score_spread":0.2640089160446881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}