{"id":"W2104675855","doi":"10.1093/nar/gkt213","title":"Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domain","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; University of Victoria","funders":"Canadian Institutes of Health Research","keywords":"Chromatin; Biology; MECP2; Cell biology; Molecular biology; DNA; Nucleosome; Mutant; Genetics; Gene; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002803748,0.00092041,0.000361858,0.0005026217,0.0002109058,0.0004328838,0.0005732515,0.0006757221,0.002489302],"category_scores_gemma":[0.0002768594,0.0004474762,0.0005184099,0.0001948438,0.0006311842,0.0002414885,0.0005606287,0.001411369,0.0007071674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004444208,"about_ca_system_score_gemma":0.0003083316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002079786,"about_ca_topic_score_gemma":0.002028729,"domain_scores_codex":[0.9994628,0.00007562867,0.00007526833,0.0001525282,0.0001332147,0.0001005059],"domain_scores_gemma":[0.9993489,0.0001414111,0.0001791353,0.00008342214,0.00003566657,0.0002114413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007030716,0.00001899867,0.00005824635,0.00001554836,0.000005962173,0.00005743899,0.000009764232,0.00004069291,0.9995134,0.00003719017,0.00001454826,0.0001578637],"study_design_scores_gemma":[0.00001296185,0.000160224,0.00178455,0.000005787827,0.00001383684,0.0003150018,0.00002029963,0.0006580229,0.9961526,0.00002680964,0.0008446507,0.000005283726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921691,0.0008324192,0.004576385,0.0001229509,0.00007562073,0.00003296833,0.001231517,0.0001629527,0.0007961052],"genre_scores_gemma":[0.9862604,0.0005444787,0.002795649,0.00007750907,0.00002030929,0.00009838965,0.001987035,0.0002029782,0.008013197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002489302,"threshold_uncertainty_score":0.008327544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03224837676525457,"score_gpt":0.318558488823911,"score_spread":0.2863101120586564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}