{"id":"W2104694017","doi":"10.1261/rna.2760705","title":"Biochemical and genomic analysis of substrate recognition by the double-stranded RNA binding domain of yeast RNase III","year":2005,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Science Foundation","keywords":"Endoribonuclease; Biology; RNA; Ribonuclease III; RNase P; RNA silencing; Biochemistry; Cell biology; RNA-binding protein; Saccharomyces cerevisiae; RNase H; Molecular biology; Yeast; RNA interference; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002483998,0.00009817434,0.0001779129,0.00005611527,0.00003995023,0.000009930166,0.0001126698,0.0001082233,0.00005071222],"category_scores_gemma":[0.000008336896,0.00007650527,0.0001123001,0.0001355032,0.00007660319,0.000003253257,0.00002290532,0.00004341672,0.00000208365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006327051,"about_ca_system_score_gemma":0.00001671661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003124675,"about_ca_topic_score_gemma":0.00001991498,"domain_scores_codex":[0.9993271,0.00004046132,0.0002317619,0.0001883764,0.00008767583,0.0001246507],"domain_scores_gemma":[0.9995736,0.00001012508,0.0001443884,0.0001931257,0.00003400891,0.00004472817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000215837,0.00003028901,0.00005083409,0.000009582875,0.0002749698,3.055033e-7,0.00005900452,0.000007681994,0.9935845,0.00001874771,0.00007817405,0.005670054],"study_design_scores_gemma":[0.0005742261,0.00005050203,0.0002023667,0.00001046107,0.0002251495,0.000002833858,0.00007788335,0.00002413166,0.9984024,0.00007147778,0.000266812,0.00009179927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978804,0.0006735033,0.0006401413,0.00008293328,0.00001666085,0.0001216117,0.0001048001,0.000003259099,0.0004767133],"genre_scores_gemma":[0.9988006,0.0002529507,0.0006316653,0.00002570598,0.00005078134,0.000008731869,0.0001349263,0.000009061296,0.00008553996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005578255,"threshold_uncertainty_score":0.3119794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01480805730723963,"score_gpt":0.2351754452816395,"score_spread":0.2203673879743998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}