{"id":"W2104694017","doi":"10.1261/rna.2760705","title":"Biochemical and genomic analysis of substrate recognition by the double-stranded RNA binding domain of yeast RNase III","year":2005,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Science Foundation","keywords":"Endoribonuclease; Biology; RNA; Ribonuclease III; RNase P; RNA silencing; Biochemistry; Cell biology; RNA-binding protein; Saccharomyces cerevisiae; RNase H; Molecular biology; Yeast; RNA interference; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009218761,0.0003018723,0.0002151356,0.0002184602,0.000108198,0.0002334439,0.0001833919,0.0001848329,0.0005258432],"category_scores_gemma":[0.0002018969,0.000160497,0.0003277736,0.0001999803,0.0001554182,0.00007798563,0.0001045046,0.0003587017,0.0003700739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003494288,"about_ca_system_score_gemma":0.0001599148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001699128,"about_ca_topic_score_gemma":0.001523977,"domain_scores_codex":[0.9998771,0.00001976102,0.00001216855,0.00002697052,0.00004139364,0.00002261202],"domain_scores_gemma":[0.999777,0.00005504442,0.00007143447,0.00002636186,0.00002809922,0.0000420206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003462625,0.00001505375,0.0002613536,0.00001238087,0.000003445159,0.000020803,0.00000694053,0.00008901033,0.9991854,0.00002902857,0.000007435521,0.0003344654],"study_design_scores_gemma":[0.0000099339,0.0001905738,0.02394639,0.000006356192,0.00002589988,0.0002841687,0.00005508582,0.00198717,0.9716623,0.00007190982,0.001752581,0.00000754653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945874,0.0006425409,0.003189963,0.00005133855,0.00001094811,0.00001372896,0.0009368515,0.00003928118,0.0005279251],"genre_scores_gemma":[0.9931651,0.0003919175,0.003168744,0.0000424945,0.000005477195,0.00002192874,0.00223452,0.00002541434,0.0009444839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001699128,"threshold_uncertainty_score":0.00337851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01480805730723963,"score_gpt":0.2351754452816395,"score_spread":0.2203673879743998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}