{"id":"W2104736000","doi":"10.1105/tpc.015396","title":"A Tale of Three Cell Types: Alkaloid Biosynthesis Is Localized to Sieve Elements in Opium Poppy","year":2003,"lang":"en","type":"article","venue":"The Plant Cell","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":192,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Opium Poppy; Sanguinarine; Benzylisoquinoline; Biology; Papaveraceae; Biochemistry; Papaver; Alkaloid; Poppy; Berberine; Thebaine; Biosynthesis; Enzyme; Botany; Codeine; Morphine; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004961403,0.0001487653,0.0003130979,0.0001439723,0.00003032552,0.000009649595,0.0002037972,0.00006668944,0.001145874],"category_scores_gemma":[0.00007188783,0.00009894917,0.00009038876,0.0003709901,0.00004786862,0.0000249449,0.00006869435,0.0001921796,0.0003829641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003838509,"about_ca_system_score_gemma":0.0001048868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000474515,"about_ca_topic_score_gemma":0.0002417621,"domain_scores_codex":[0.9986492,0.00007618434,0.0003086124,0.000225232,0.0003515119,0.0003892128],"domain_scores_gemma":[0.9991679,0.0001699349,0.00005789764,0.0004216159,0.00004749864,0.0001351805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001527742,0.001902251,0.04174238,0.0007777452,0.0001776551,0.0002715345,0.002599006,0.0000294796,0.9005529,0.0002070435,0.04668001,0.003532255],"study_design_scores_gemma":[0.001942289,0.0003840908,0.0009015842,0.0001280056,0.00006538999,0.00002415263,0.0004186383,0.0002775763,0.9076022,0.0001419329,0.08793552,0.0001786327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9528597,0.0004313872,0.00008142182,0.0009347062,0.0000618038,0.0006645793,0.0001107708,0.00001681155,0.04483881],"genre_scores_gemma":[0.9916551,0.0001655856,0.0008179084,0.0007230684,0.00003923262,0.00002204055,0.00001905601,0.00002498315,0.006533042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04125552,"threshold_uncertainty_score":0.9997672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02922145636826673,"score_gpt":0.2705306371953778,"score_spread":0.2413091808271111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}