{"id":"W2104749274","doi":"10.1593/neo.06739","title":"Androgen Induces Adaptation to Oxidative Stress in Prostate Cancer: Implications for Treatment with Radiation Therapy","year":2007,"lang":"en","type":"article","venue":"Neoplasia","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research; McMaster University","funders":"","keywords":"Oxidative stress; Reactive oxygen species; Superoxide dismutase; Prostate cancer; Androgen receptor; Internal medicine; Endocrinology; Catalase; Androgen deprivation therapy; Testosterone (patch); Chemistry; Cancer research; Biology; Medicine; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003341151,0.0003392179,0.0003943239,0.000328813,0.0002067981,0.0005036592,0.0003865493,0.000385954,0.001513028],"category_scores_gemma":[0.000212666,0.00009494522,0.0002704296,0.0002941158,0.0005393205,0.0003167058,0.0001848388,0.0006504711,0.0001547505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005579428,"about_ca_system_score_gemma":0.0005601982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005661721,"about_ca_topic_score_gemma":0.0009172016,"domain_scores_codex":[0.9998896,0.00004245621,0.00000632719,0.00001455297,0.0000205449,0.00002660231],"domain_scores_gemma":[0.9998659,0.00002776344,0.00004015765,0.000009426138,0.0000169873,0.00003963257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005485803,0.002193004,0.03091863,0.003025297,0.0003113149,0.003576857,0.0005702067,0.002637779,0.6822163,0.01849749,0.007073521,0.2434938],"study_design_scores_gemma":[0.0006768513,0.01471781,0.4192432,0.0005752772,0.0006423412,0.01090803,0.002009248,0.004325381,0.4129688,0.02054878,0.1132299,0.0001543119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5421293,0.417354,0.007707099,0.01685549,0.0008735849,0.0001395836,0.0004253395,0.0003018703,0.0142137],"genre_scores_gemma":[0.914527,0.08018845,0.001290513,0.0007628478,0.0004654872,0.00004445739,0.0001010809,0.00001090614,0.002609214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001513028,"threshold_uncertainty_score":0.005061626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03559997344605076,"score_gpt":0.3441756533268581,"score_spread":0.3085756798808074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}