{"id":"W2104789070","doi":"10.1074/jbc.m109913200","title":"Rac1 and Cdc42 but Not RhoA or Rho Kinase Activities Are Required for Neurite Outgrowth Induced by the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) in N1E-115 Neuroblastoma Cells","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Netrin; RHOA; Deleted in Colorectal Cancer; RAC1; Neurite; CDC42; Cell biology; Axon guidance; Biology; GTPase; PAK1; Signal transduction; Axon; Cancer; Colorectal cancer; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001297432,0.0004155681,0.0003085683,0.0002878255,0.0002932811,0.0004279418,0.0002249723,0.0002290509,0.0009486456],"category_scores_gemma":[0.0001687554,0.0003068214,0.0003105551,0.0001299106,0.0002224783,0.0001730097,0.0003068001,0.0005234645,0.0005605363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007711495,"about_ca_system_score_gemma":0.0005406835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005581799,"about_ca_topic_score_gemma":0.009250713,"domain_scores_codex":[0.9997779,0.00002260897,0.00002969069,0.00003489426,0.00007962686,0.00005530904],"domain_scores_gemma":[0.9997824,0.00002979538,0.00005828675,0.00002691365,0.00002249243,0.00008012534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004899826,0.00001315024,0.0002230937,0.00001737292,0.000002730801,0.00007146577,0.00001139262,0.00004378329,0.9992701,0.00005457239,0.00002256414,0.000220694],"study_design_scores_gemma":[0.00002733601,0.0001353793,0.0271854,0.00001193523,0.00002777629,0.0006217347,0.00006957844,0.002000973,0.9669819,0.00004042143,0.002888052,0.000009529361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970324,0.0007311608,0.0004532263,0.00006304969,0.00001035838,0.00001342425,0.0004600477,0.00004013082,0.001196143],"genre_scores_gemma":[0.9937835,0.0007039332,0.0009362031,0.00002530296,0.000003467983,0.00004385478,0.001653689,0.00002019251,0.00282992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005581799,"threshold_uncertainty_score":0.01109862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06886566076811995,"score_gpt":0.2752568383385681,"score_spread":0.2063911775704481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}