{"id":"W2104789070","doi":"10.1074/jbc.m109913200","title":"Rac1 and Cdc42 but Not RhoA or Rho Kinase Activities Are Required for Neurite Outgrowth Induced by the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) in N1E-115 Neuroblastoma Cells","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Netrin; RHOA; Deleted in Colorectal Cancer; RAC1; Neurite; CDC42; Cell biology; Axon guidance; Biology; GTPase; PAK1; Signal transduction; Axon; Cancer; Colorectal cancer; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003215652,0.0002652407,0.0004769236,0.00006067366,0.0001236794,0.00006417689,0.0004246032,0.0002302314,0.0001230054],"category_scores_gemma":[0.001165938,0.0001638579,0.0001217278,0.0003582407,0.0002172664,0.0001788306,0.0001005056,0.0007724527,0.000001432566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009665368,"about_ca_system_score_gemma":0.00004541761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009552112,"about_ca_topic_score_gemma":0.000006033365,"domain_scores_codex":[0.9980249,0.0001759362,0.0006588769,0.0004192131,0.0002705367,0.000450523],"domain_scores_gemma":[0.9977722,0.001312263,0.0006054172,0.0001102877,0.00004878491,0.0001510138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00168179,0.00016309,0.0006455389,0.00003674286,0.000004270332,0.0001354915,0.00007271447,0.00003104355,0.9953598,8.504466e-7,0.0003643004,0.001504375],"study_design_scores_gemma":[0.001390908,0.0005965423,0.001460266,0.0001090124,0.000007066795,0.0001083414,0.0001461325,0.0005437679,0.9948867,0.00001369886,0.000533578,0.0002039805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979144,0.0002815752,0.000006819552,0.001232012,0.0001702842,0.0002389276,0.0001018574,0.00001717233,0.00003692637],"genre_scores_gemma":[0.9976593,0.0009323846,0.00001990111,0.0009759039,0.0002293331,0.00003121052,8.73644e-7,0.00001816884,0.0001328987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001300394,"threshold_uncertainty_score":0.6681933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06886566076811995,"score_gpt":0.2752568383385681,"score_spread":0.2063911775704481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}