{"id":"W2104795433","doi":"10.1002/anie.201006896","title":"In Vivo Solid‐Phase Microextraction in Metabolomics: Opportunities for the Direct Investigation of Biological Systems","year":2011,"lang":"en","type":"review","venue":"Angewandte Chemie International Edition","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Solid-phase microextraction; Metabolomics; Context (archaeology); Metabolome; Organism; Computer science; Biochemical engineering; Computational biology; Chemistry; Biology; Chromatography; Mass spectrometry; Gas chromatography–mass spectrometry; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008516731,0.001090587,0.001275677,0.001355972,0.0002974547,0.001101656,0.0009708571,0.001414685,0.002277482],"category_scores_gemma":[0.0003855601,0.0004535092,0.0004407661,0.00210609,0.0006836193,0.001758544,0.0006908249,0.001507354,0.004099334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007276055,"about_ca_system_score_gemma":0.0006303252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00055082,"about_ca_topic_score_gemma":0.001058327,"domain_scores_codex":[0.9997445,0.00004541595,0.00001518151,0.00005702981,0.0001142714,0.00002364718],"domain_scores_gemma":[0.9997656,0.0001113619,0.00002706795,0.00001540358,0.00006198893,0.00001861054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006369129,0.000165117,0.0002276375,0.01320287,0.00007604581,0.000436056,0.00008709496,0.0009604153,0.08805842,0.01029134,0.01451844,0.871913],"study_design_scores_gemma":[0.00001530126,0.0001931296,0.0008004603,0.001078287,0.000071173,0.001722755,0.00009071464,0.000580067,0.03936233,0.004493337,0.9515431,0.00004923742],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008866583,0.9888754,0.005355083,0.00036914,0.0003791516,0.00001754059,0.00004203316,0.00004470636,0.004030282],"genre_scores_gemma":[0.003626559,0.98866,0.004516712,0.0002092141,0.0001839062,0.00002290662,0.00007129488,0.000008492043,0.002701007],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002277482,"threshold_uncertainty_score":0.007618964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.123876742915825,"score_gpt":0.3610899259006582,"score_spread":0.2372131829848332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}