{"id":"W2104795433","doi":"10.1002/anie.201006896","title":"In Vivo Solid‐Phase Microextraction in Metabolomics: Opportunities for the Direct Investigation of Biological Systems","year":2011,"lang":"en","type":"review","venue":"Angewandte Chemie International Edition","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Solid-phase microextraction; Metabolomics; Context (archaeology); Metabolome; Organism; Computer science; Biochemical engineering; Computational biology; Chemistry; Biology; Chromatography; Mass spectrometry; Gas chromatography–mass spectrometry; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005629085,0.0002515348,0.0006557046,0.000240709,0.00003518672,0.00002198669,0.0002670477,0.0003090311,0.00003023932],"category_scores_gemma":[0.0002311494,0.0001831387,0.0002539679,0.0001145652,0.0001178681,0.0000176766,0.00007577176,0.0001464559,8.439704e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007196954,"about_ca_system_score_gemma":0.0001038198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007964027,"about_ca_topic_score_gemma":0.00004164414,"domain_scores_codex":[0.9986278,0.00007541399,0.0006752711,0.0003437244,0.0001082006,0.0001695907],"domain_scores_gemma":[0.9989352,0.0001429197,0.0005475641,0.0001856196,0.00015876,0.0000299006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001399607,0.001750236,0.0002441031,0.01149508,0.005400978,0.00003726901,0.0006505652,0.00004581675,0.6949692,0.0117897,0.1153362,0.1568813],"study_design_scores_gemma":[0.0004521953,0.00008956584,0.000007439499,0.0004759976,0.0001238563,0.00001187491,0.0001139802,0.000009027084,0.1528004,0.0001337873,0.8456095,0.00017234],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007627514,0.9934453,0.000926373,0.0001002025,0.002125223,0.0007920155,0.0009851352,0.00000668498,0.0008562737],"genre_scores_gemma":[0.005016296,0.9912658,0.00008384045,0.00004591908,0.001109096,0.0006375029,0.001427672,0.00002268765,0.0003911309],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7302734,"threshold_uncertainty_score":0.7468179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.123876742915825,"score_gpt":0.3610899259006582,"score_spread":0.2372131829848332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}