{"id":"W2104827888","doi":"10.1038/nature07182","title":"PRDM16 controls a brown fat/skeletal muscle switch","year":2008,"lang":"en","type":"article","venue":"Nature","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":2324,"is_retracted":false,"has_abstract":false,"ca_institutions":"Stem Cell Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Arthritis and Musculoskeletal and Skin Diseases; American Heart Association","keywords":"PRDM16; Adipogenesis; Biology; MYF5; Brown adipose tissue; Endocrinology; Internal medicine; Progenitor cell; White adipose tissue; Skeletal muscle; Myogenin; Cell biology; MyoD; Adipose tissue; Myogenesis; Stem cell; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004413257,0.0007837755,0.0005055657,0.0004897527,0.0003636617,0.000851665,0.0008147008,0.0008652239,0.00669645],"category_scores_gemma":[0.0003882321,0.0006910998,0.0005525761,0.0002136381,0.0009396605,0.0005419364,0.0009774459,0.001755167,0.001793203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005346457,"about_ca_system_score_gemma":0.0003194413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000433746,"about_ca_topic_score_gemma":0.001033487,"domain_scores_codex":[0.9995319,0.00005008697,0.00004094761,0.0002069619,0.00008603019,0.00008406472],"domain_scores_gemma":[0.9994917,0.00005537495,0.0001911353,0.00008577327,0.00003064515,0.0001453834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005655786,0.0000304995,0.001208926,0.00005854198,0.00002473501,0.0002468398,0.00002820364,0.00009675433,0.9918011,0.001165978,0.0004985226,0.004274344],"study_design_scores_gemma":[0.0002378249,0.0003433752,0.03675993,0.00007468463,0.00008179482,0.002093292,0.0001662924,0.001525738,0.9306674,0.001533135,0.02647647,0.00004002681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758749,0.003842762,0.0076673,0.00147491,0.00101971,0.00003542909,0.001853977,0.001076484,0.007154538],"genre_scores_gemma":[0.9750128,0.00157824,0.004905344,0.0005032324,0.0000979049,0.00005321271,0.001029033,0.00053781,0.01628248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00669645,"threshold_uncertainty_score":0.02240193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01176718250229983,"score_gpt":0.2719017327168072,"score_spread":0.2601345502145074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}