{"id":"W2104833083","doi":"10.1139/y09-049","title":"High molecular weight FGF-2 promotes postconditioning-like cardioprotection linked to activation of the protein kinase C isoforms Akt and p70 S6 kinaseThis article is one of a selection of papers published in a special issue celebrating the 125th anniversary of the Faculty of Medicine at the University of Manitoba.","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Cardioprotection; Protein kinase B; Gene isoform; P70-S6 Kinase 1; Selection (genetic algorithm); Cell biology; Protein kinase A; Phosphorylation; PI3K/AKT/mTOR pathway; Kinase; Chemistry; Biology; Medicine; Biochemistry; Internal medicine; Signal transduction; Gene; Computer science; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019574,0.0006841355,0.0002992603,0.0002295238,0.00009672824,0.0002215562,0.0002034279,0.0002372932,0.001282179],"category_scores_gemma":[0.0001014257,0.0001129764,0.0003400887,0.0001426648,0.0002413186,0.0002369848,0.0001878316,0.0005505481,0.0001990796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000222353,"about_ca_system_score_gemma":0.0003003287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005085924,"about_ca_topic_score_gemma":0.0008324081,"domain_scores_codex":[0.9998912,0.00001510776,0.000008312926,0.00001775551,0.00002756719,0.00004011912],"domain_scores_gemma":[0.9998858,0.00000951736,0.00004680974,0.000009084906,0.000009455046,0.00003934902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005676043,0.0001340616,0.0001075278,0.00005147162,0.000007397688,0.00005697671,0.00001461438,0.00003161123,0.9973118,0.00005549192,0.00006211192,0.001599372],"study_design_scores_gemma":[0.0001116884,0.001964477,0.01133215,0.00001070712,0.00003057814,0.0002604864,0.00002765821,0.0008343901,0.9839188,0.00006608546,0.001435243,0.000007739908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942014,0.002373667,0.001779564,0.0000995424,0.00008086507,0.00004794694,0.0001844774,0.0001013302,0.001131263],"genre_scores_gemma":[0.9941972,0.001410621,0.00162328,0.00006861926,0.00004478591,0.0000596996,0.0003796093,0.00001705744,0.002198997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001282179,"threshold_uncertainty_score":0.004289329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006188689857971275,"score_gpt":0.2194573315822049,"score_spread":0.2132686417242336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}