{"id":"W2104863570","doi":"10.1128/ec.00138-14","title":"Membrane Fluidity and Temperature Sensing Are Coupled via Circuitry Comprised of Ole1, Rsp5, and Hsf1 in Candida albicans","year":2014,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Candida albicans; HSF1; Biology; Heat shock; Heat shock protein; Heat shock factor; Ubiquitin ligase; Saccharomyces cerevisiae; Membrane fluidity; Cell biology; Hsp70; Biochemistry; Microbiology; Yeast; Ubiquitin; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002206877,0.0001498918,0.0002355849,0.0000544936,0.00005302483,0.00001977761,0.00009120328,0.0001557772,0.00001748537],"category_scores_gemma":[0.0000480825,0.0001406105,0.00003360632,0.00009486314,0.0001429662,0.000002410005,0.0001182861,0.0001605754,0.000001771313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008977194,"about_ca_system_score_gemma":0.00004535385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001505432,"about_ca_topic_score_gemma":0.000197411,"domain_scores_codex":[0.9989874,0.000097607,0.000188078,0.0003323515,0.0001505616,0.0002440347],"domain_scores_gemma":[0.9994563,0.00004007418,0.00005707226,0.0002497981,0.00007026796,0.0001264754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000559838,0.00004936851,0.03529136,0.0001701125,0.00001241462,0.000007124814,0.00006043853,0.00006299219,0.9636155,0.000003677627,0.00009637321,0.0005746434],"study_design_scores_gemma":[0.001802601,0.0002542365,0.2219641,0.0000664033,0.00002009776,0.00003172828,0.0001289613,0.007219486,0.7678837,0.000051836,0.0002995973,0.0002772311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99771,0.001027371,0.0001320293,0.00009089526,0.00006320273,0.0001575103,0.00001475729,0.000004680481,0.0007995623],"genre_scores_gemma":[0.9989758,0.0003110497,0.0001746926,0.00009978352,0.00009245797,0.000001591771,0.00004261528,0.00001759007,0.0002844672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1957318,"threshold_uncertainty_score":0.573393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005379933140597564,"score_gpt":0.2068913424409179,"score_spread":0.2015114093003203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}