{"id":"W2104863570","doi":"10.1128/ec.00138-14","title":"Membrane Fluidity and Temperature Sensing Are Coupled via Circuitry Comprised of Ole1, Rsp5, and Hsf1 in Candida albicans","year":2014,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Candida albicans; HSF1; Biology; Heat shock; Heat shock protein; Heat shock factor; Ubiquitin ligase; Saccharomyces cerevisiae; Membrane fluidity; Cell biology; Hsp70; Biochemistry; Microbiology; Yeast; Ubiquitin; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112222,0.0003383039,0.0002087332,0.0001783425,0.0003175327,0.0004611478,0.0003820964,0.0003710756,0.0006065273],"category_scores_gemma":[0.000143493,0.0001688888,0.0003397431,0.0001421412,0.000314024,0.0003454106,0.000483251,0.0005147689,0.0002415013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005236492,"about_ca_system_score_gemma":0.0003110002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001326203,"about_ca_topic_score_gemma":0.001210778,"domain_scores_codex":[0.9998723,0.00001381662,0.00001341047,0.00003323026,0.00003941741,0.00002771449],"domain_scores_gemma":[0.9999237,0.000009032017,0.00002527761,0.000009489298,0.000009634102,0.00002284367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001394891,0.00001440095,0.0005507797,0.00003795418,0.000005428227,0.00008353053,0.00001499266,0.0002597722,0.9970704,0.0003260254,0.00003411248,0.001462985],"study_design_scores_gemma":[0.00002289669,0.0001345243,0.0132864,0.00001507547,0.00002377171,0.0002226926,0.00007236331,0.006549718,0.9771001,0.0002464266,0.00230603,0.00001989128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938046,0.001896855,0.00288183,0.0001404079,0.00003647804,0.00001177956,0.0002653053,0.0001108173,0.0008518654],"genre_scores_gemma":[0.9962799,0.0007507125,0.001796082,0.00006414852,0.000004867336,0.00001537582,0.0002500766,0.0000130933,0.0008256874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001326203,"threshold_uncertainty_score":0.003799319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005379933140597564,"score_gpt":0.2068913424409179,"score_spread":0.2015114093003203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}