{"id":"W2104881676","doi":"10.1016/j.jchromb.2008.10.016","title":"Demonstration of the interaction of transforming growth factor beta 2 and type X collagen using a modified tandem affinity purification tag","year":2008,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Transforming growth factor; Transforming growth factor beta; Chemistry; Protein precursor; Translation (biology); Molecular biology; Gene; Tandem affinity purification; Biology; Cell biology; Affinity chromatography; Biochemistry; Messenger RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009569852,0.00006864559,0.0001293154,0.00008116,0.00005409108,0.000006010799,0.00009089292,0.00006810435,0.000002654882],"category_scores_gemma":[0.00003840856,0.00005257704,0.0001254842,0.0001544748,0.00009838598,0.00001632199,0.000009745392,0.00004479617,2.472873e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005520049,"about_ca_system_score_gemma":0.0001190591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006274646,"about_ca_topic_score_gemma":0.000003472559,"domain_scores_codex":[0.9993398,0.00005412681,0.0003347536,0.00006814576,0.0001443708,0.00005886308],"domain_scores_gemma":[0.9991548,0.00001588429,0.0004651375,0.00008910322,0.0002414164,0.00003364413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008764529,0.00006345339,0.0522908,0.00003378044,0.00008088933,5.603374e-7,0.0001628349,0.00009870657,0.9470156,0.00001419064,0.00002348102,0.0001280402],"study_design_scores_gemma":[0.0003172284,0.0001384678,0.06996392,0.00006321254,0.00005687841,0.0000792752,0.00009927831,0.00006334027,0.92911,0.00002627867,0.00003036162,0.00005176853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970726,0.0006384388,0.002041617,0.00001439326,0.00008314438,0.00008407524,0.000006829352,0.000001703924,0.0000572025],"genre_scores_gemma":[0.9992007,0.0001665879,0.0005692018,0.000006416573,0.00004610323,5.001368e-7,0.00000284085,0.000006274609,0.000001365829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01790562,"threshold_uncertainty_score":0.214403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02898323823621336,"score_gpt":0.2627701201779461,"score_spread":0.2337868819417327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}