{"id":"W2104887197","doi":"10.1096/fj.07-8983com","title":"A peptide inhibitor of HIV‐1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Simon Fraser University; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Michael Smith Health Research BC","keywords":"Epitope; Chemistry; Mimotope; Peptide; Trimer; Binding site; Molecular mimicry; Stereochemistry; Biochemistry; Antibody; Phage display; Biology; Dimer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001816748,0.0005194814,0.000543147,0.0002094215,0.0001338581,0.000347823,0.0004765615,0.0005521525,0.001517575],"category_scores_gemma":[0.0002634872,0.0002418975,0.0002403244,0.0001533124,0.0002069352,0.0001462278,0.0001840134,0.0007203779,0.0004735141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004170869,"about_ca_system_score_gemma":0.0002383319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006023995,"about_ca_topic_score_gemma":0.0008328917,"domain_scores_codex":[0.9997227,0.00005635341,0.00001517306,0.00003722375,0.0000798308,0.00008871996],"domain_scores_gemma":[0.9998815,0.00003889591,0.00001987465,0.00001486795,0.0000127062,0.00003205574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002061326,0.0001012237,0.0002386992,0.00004591599,0.00001202785,0.00006171416,0.00000973841,0.0001474834,0.9972971,0.0000551525,0.00005844334,0.00176636],"study_design_scores_gemma":[0.0002964736,0.003581625,0.01252725,0.00002382969,0.00005403913,0.001846128,0.00002077145,0.002690874,0.9724783,0.00006261915,0.006405671,0.00001234675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99701,0.0008271657,0.0006639123,0.0000496998,0.00002100628,0.00004667728,0.00008838966,0.00004470967,0.001248261],"genre_scores_gemma":[0.9960366,0.0004783492,0.00123468,0.000121669,0.00001693713,0.00005890637,0.0004733269,0.00001492383,0.001564612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001517575,"threshold_uncertainty_score":0.005076766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01726317260790123,"score_gpt":0.2785102030932611,"score_spread":0.2612470304853599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}