{"id":"W2104920168","doi":"10.1139/y09-125","title":"Plasma membrane subdomain partitioning of Lck in primary human T lymphocytes","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto Nacional de Perinatología","keywords":"T-cell receptor; CD28; Cell biology; Dephosphorylation; Raft; Phosphorylation; CD3; Tyrosine kinase; Lipid raft; Biology; Signal transduction; T cell; Chemistry; Immunology; CD8; Antigen; Phosphatase; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001000776,0.0001829408,0.0001865565,0.000331619,0.0002501164,0.0003507267,0.0001107314,0.0001879101,0.001310009],"category_scores_gemma":[0.000125008,0.0001599597,0.0002510264,0.0002747322,0.0001277025,0.0001877004,0.000177276,0.0003719862,0.0008175864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00031906,"about_ca_system_score_gemma":0.0001452141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001520699,"about_ca_topic_score_gemma":0.001600243,"domain_scores_codex":[0.9998536,0.00001786479,0.00001041556,0.00004201661,0.00003241674,0.00004370528],"domain_scores_gemma":[0.9999514,0.00001462211,0.000005434616,0.000008377399,0.000009994472,0.00001017119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001568254,0.000009038526,0.0002659758,0.00002490332,0.000003024099,0.00006140175,0.00002470518,0.00002087426,0.9986032,0.00002873068,0.00003275465,0.0007687009],"study_design_scores_gemma":[0.00005153417,0.0004872849,0.04104815,0.00001572741,0.00005574415,0.001486961,0.0001929582,0.0009087461,0.9513507,0.0001955286,0.004194118,0.00001253161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882719,0.004778624,0.003257008,0.00009477722,0.00002953456,0.00003998538,0.0009212606,0.00006432518,0.002542502],"genre_scores_gemma":[0.9927181,0.001948715,0.001653481,0.00008238967,0.00001892445,0.00004994594,0.001639196,0.00002376827,0.001865425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001520699,"threshold_uncertainty_score":0.004382432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00880400131678121,"score_gpt":0.2291779437081076,"score_spread":0.2203739423913263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}