{"id":"W2105129779","doi":"10.1016/j.febslet.2014.08.012","title":"Expression of type I collagen and tenascin C is regulated by actin polymerization through MRTF in dedifferentiated chondrocytes","year":2014,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Arthritis Network; Canadian Institutes of Health Research; U.S. Department of Defense; U.S. Army; University of Toronto; Natural Sciences and Engineering Research Council of Canada","keywords":"Cell biology; Chemistry; Gene expression; Actin; Fibroblast; SOX9; Cytochalasin D; Molecular biology; Cytoskeleton; Biology; Gene; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001284322,0.0002024454,0.0001852771,0.0002441136,0.0001787994,0.0002424031,0.00008951018,0.0001693236,0.0005876521],"category_scores_gemma":[0.00009030123,0.0001388041,0.0002222983,0.0001164636,0.0001388874,0.0001653301,0.0001289519,0.0003127994,0.000198625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001630833,"about_ca_system_score_gemma":0.000116092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027305,"about_ca_topic_score_gemma":0.001701277,"domain_scores_codex":[0.9998946,0.00001446108,0.00001619432,0.00002406829,0.00002885416,0.00002180128],"domain_scores_gemma":[0.9998976,0.00001217436,0.00002802214,0.00001205103,0.00002396801,0.00002618133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003748809,0.000005549309,0.0002408241,0.00001073851,0.000001464019,0.0000342833,0.00001443115,0.000006555661,0.9993767,0.000009630852,0.000003855588,0.0002585036],"study_design_scores_gemma":[0.00001053276,0.0002176983,0.03430307,0.000006959126,0.00001804354,0.000366336,0.0001303602,0.0003779046,0.9623963,0.00002525918,0.002141847,0.000005653749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958198,0.001426357,0.001715256,0.0000394442,0.00001493679,0.0000117257,0.0002048731,0.00001353955,0.0007541095],"genre_scores_gemma":[0.9938712,0.001033807,0.00134323,0.00003895531,0.00001013496,0.00002597513,0.0005216461,0.00001020802,0.003144804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001027305,"threshold_uncertainty_score":0.002042592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008368000054170661,"score_gpt":0.2275310149446496,"score_spread":0.2191630148904789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}